Evidence map›Paper›PMID 39414394›Full record

ArticlePhysiological reports2024

Characterization of a novel variant in KCNJ16, encoding K

Biyang Xu, Vladislav Levchenko, Ruslan Bohovyk, Ameneh Ahrari, Aron M Geurts, Valerie Sency, Baozhong Xin, Heng Wang, Alexander Staruschenko

Abstract readCase Reports
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Biyang XuDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Vladislav LevchenkoDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Ruslan BohovykDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Ameneh AhrariDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Aron M GeurtsDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Valerie SencyDDC Clinic for Special Needs Children, Middlefield, Ohio, USA.
Baozhong XinDDC Clinic for Special Needs Children, Middlefield, Ohio, USA.
Heng WangDDC Clinic for Special Needs Children, Middlefield, Ohio, USA.
Alexander StaruschenkoDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-5190-8356

Funding

Renal ion channels in the control of blood pressureR35HL135749 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI STARUSCHENKO, ALEXANDER · 2017 to 2023
$3.6M
Training in Research on Vascular Inflammation and InjuryT32HL160529 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI Sarah Y Yuan · 2022 to 2026
$1.1M
Transport and metabolism in the kidneyI01BX004024 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI STARUSCHENKO, ALEXANDER · 2019 to 2025
–
BLRD VA I01 BX004024NHLBI NIH HHS R35 HL135749NHLBI NIH HHS T32 HL160529
6 · The paper itself

Abstract

The essential role of the inwardly rectifying potassium channel K

Indexed as

Kir5.1 ChannelPotassium Channels, Inwardly RectifyingAnimalsCHO CellsCricetulusHumansMaleMutationRatsRats, Inbred DahlKCNJ16 protein, humanKir5.1 ChannelPotassium Channels, Inwardly RectifyingKCNJ16 mutationKir5.1Kir channelspotassium channelsalt‐sensitive hypertension

Identifiers

PMID39414394
PMCPMC11483507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.