Evidence map›Paper›PMID 39414315›Full record

ArticleBMJ mental health2024

Risk of repeat self-harm among individuals presenting to healthcare services: development and validation of a clinical risk assessment model (OxSET).

Seena Fazel, Maria D L A Vazquez-Montes, Tyra Lagerberg, Yasmina Molero, Jane Walker, Michael Sharpe, Henrik Larsson, Bo Runeson, Paul Lichtenstein, Thomas R Fanshawe

Abstract readValidation Study
In one paragraph

Article in BMJ mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seena FazelDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK seena.fazel@psych.ox.ac.uk.ORCID http://orcid.org/0000-0002-5383-5365
Maria D L A Vazquez-MontesNuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, UK.
Tyra LagerbergDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-2480-0216
Yasmina MoleroDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Jane WalkerDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Michael SharpeDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Bo RunesonDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Thomas R FanshaweNuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundA self-harm episode is a major risk factor for repeat self-harm. Existing tools to assess and predict repeat self-harm have major methodological limitations, and few are externally validated.

objectiveTo develop and validate a risk assessment model of repeat self-harm up to 6 months after an episode of non-fatal self-harm that resulted in an emergency visit to hospital or specialised care.

methodsUsing Swedish national registers, we identified 53 172 people aged≥10 years who self-harmed during 2008-2012. We allocated 37 523 individuals to development (2820 or 7.5% repeat self-harm incidents within 6 months) and 15 649 to geographic validation (1373 repeat episodes) samples, based on region of residence. In a temporal validation of people who self-harmed during 2018-2019, we identified 25 036 individuals (2886 repeat episodes). We fitted a multivariable accelerated failure time model to predict risk of repeat self-harm.

findingsIn the external validations (n=40 685), rates of repeat self-harm were 8.8%-11.5% over 6 months. The final model retained 17 factors. Calibration and discrimination were similar in both validation samples, with observed-to-expected ratio=1.15 (95% CI=1.09 to 1.21) and c-statistic=0.72 (95% CI=0.70 to 0.73) in the geographical validation. At 6 months and a 10% risk cut-off, sensitivity was 51.5% (95% CI=48.8% to 54.2%) and specificity was 80.7% (95% CI=80.1% to 81.4%) in geographic validation; corresponding values were 56.9% (95% CI=55.1% to 58.7%) and 76.0% (95% CI=75.5% to 76.6%) in temporal validation. Discrimination was slightly worse at the 1-month prediction horizon (c-statistics of 0.66-0.68).

conclusionsUsing mostly routinely collected data, simple risk assessment models and tools can provide acceptable levels of accuracy for repeat of self-harm. CLINICAL IMPLICATIONS: This risk model (OXford SElf-harm repeat tool) may assist clinical decision-making.

Indexed as

Self-Injurious BehaviorAdolescentAdultAgedChildEmergency Service, HospitalFemaleHumansMaleMiddle AgedRecurrenceRegistriesRisk AssessmentRisk FactorsSwedenYoung AdultData Interpretation, StatisticalSuicide & self-harm

Identifiers

PMID39414315
PMCPMC11481133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.