ArticleContemporary clinical trials2024
Effectiveness and costs of the recruitment strategies used in the MetA-Bone trial, a randomized clinical trial to test the effects of soluble corn fiber supplementation for 1 year in children.
Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02916862 (Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents
Who cites it
1 citing paper in PubMed.
- Comparing in-person and online recruitment methods in a prospective pediatric cohort study.Pediatric research · 2026Article
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13 authors.
Funding
Abstract
backgroundPediatric recruitment into clinical trials is very challenging. A recruitment plan was designed to recruit healthy children (9-14 years) in a trial testing the 1-year effect of corn soluble fiber supplementation on bone mass. We evaluated the effectiveness and costs of the recruitment strategies used in this trial.
methodsThe recruitment plan included "Traditional" (mailings, flyers, posters, visits, snowball, etc.) or "Online" (email campaigns, social media, website, etc.) strategies. All strategies led to the pre-screening online form, which asked how they learned about the study. This analysis includes the number of pre-screenings and enrollment (consents signed), ineligibility, socio-demographics, and costs per strategy. Differences were analyzed using ANOVA or chi-square.
results649 individuals completed the pre-screening; 37.1 % came from "Traditional", 46.7 % from "Online", 2.6 % from "Other", and 13.6 % from "Unknown" strategies. The most successful strategies were related to Florida International University (posting flyers around campus and email campaigns). The main reasons for ineligibility were obesity (38.9 %) or outside the age range (22.7 %). A total of 48.4 % of the children enrolled came from "Traditional", 50.2 % from "Online", and 1.4 % from "Other" strategies. The cost per screened participant was $1112 for "Traditional" and $512 for "Online" strategies, and the cost per enrolled participant was $2704 for "Traditional" and $1454 for "Online" strategies. The highest costs were staff salary.
conclusion"Online" strategies were more effective and had a lower implementation cost than "Traditional" strategies, although these were also important in achieving the recruitment goal. Future pediatric trials should consider some of these strategies and their costs. CLINICALTRIALS: gov registry number: NCT02916862.
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