Evidence map›Paper›PMID 39413818›Full record

ArticlePhysics in medicine and biology2024

Modeling the oxygen effect in DNA strand break induced by gamma-rays with TOPAS-nBio.

Naoki D-Kondo, Thongchai A M Masilela, Wook-Geun Shin, Bruce Faddegon, Jay LaVerne, Jan Schuemann, Jose Ramos-Mendez

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naoki D-KondoDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, United States of America.ORCID 0000-0002-4410-1925
Thongchai A M MasilelaDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, United States of America.ORCID 0000-0002-1717-6761
Wook-Geun ShinDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-8622-1888
Bruce FaddegonDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, United States of America.ORCID 0000-0002-4573-1582
Jay LaVerneRadiation Laboratory and Department of Physics and Astronomy, University of Notre Dame, Notre Dame, IN 46556, United States of America.
Jan SchuemannDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-7554-8818
Jose Ramos-MendezDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, United States of America.ORCID 0000-0002-8106-5142

Funding

TOPAS - nBio, a Monte Carlo tool for radiation biology researchR01CA187003 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUEMANN, JAN PATRICK OSCAR · 2015 to 2024
$4.8M
Using experimentally-guided multi-scale modeling to determining the mechanism of FLASH tissue sparingR01CA266419 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUEMANN, JAN PATRICK OSCAR · 2022 to 2025
$3.3M
NCI NIH HHS R01 CA187003NCI NIH HHS R01 CA266419
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Breaks, Double-StrandedGamma RaysMonte Carlo MethodOxygenDNADNAOxygenchemical repairDNA damage simulationMonte Carlooxygen effectsplasmidsTOPAStrack-structure

Identifiers

PMID39413818
PMCPMC12054022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.