ArticleClinics (Sao Paulo, Brazil)2024
Comprehensive diagnosis of advanced-stage breast cancer: exploring detection methods, molecular subtypes, and demographic influences - A cross-sectional study.
Article in Clinics (Sao Paulo, Brazil), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The effect of education with WhatsApp application on women's health beliefs, self-efficacy levels, and regular mammography behavior: a randomized controlled experimental trial.Revista da Associacao Medica Brasileira (1992) · 2025Trial
- An 8-gene diabetes-related signature predicts survival and immunotherapy response in breast cancer.Clinics (Sao Paulo, Brazil) · 2026Article
- Evaluation of routine four-quadrant re-excision in patients undergoing breast-conserving surgery.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Independent prognostic ımpact of perineural ınvasion in breast cancer patients with residual disease after neoadjuvant chemotherapy.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Re: Is cancer back? Psychological issues faced by survivors of breast cancer.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Mammography at 40 saves lives: new evidence demands a global shift in breast cancer screening guidelines in Brazil.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Development and validation of the Breast Cancer Myths Scale for women.Revista da Associacao Medica Brasileira (1992) · 2025Article
- The prognostic value of platelet count and lymphocyte-to-monocyte ratio, Ki-67, and Nottingham indexes in early-stage breast cancer.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Combination of cyclin-dependent kinase 4/6 inhibitors and renin-angiotensin system inhibitors in breast cancer treatment: a promising therapeutic approach.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Factors associated with recurrence in operable breast cancer patients undergoing surgery as the sole treatment modality.Acta cirurgica brasileira · 2025Article
- Breast cancer radiotherapy: analysis of unintended internal mammary node doses and influencing factors.Revista da Associacao Medica Brasileira (1992) · 2025Article
- The relationship of out-of-pocket expenses to quality of life and disease coping in breast cancer patients receiving chemotherapy.Revista da Associacao Medica Brasileira (1992) · 2025Article
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11 authors.
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Abstract
backgroundBrazil faces notable Breast Cancer (BC) mortality despite lower incidence rates versus developed countries. Despite guidelines from medical societies, Brazilian public policy recommends biennial mammographic screening for women aged 50 to 69. This study investigates sociodemographic and clinical factors related to BC detection methods and clinical stage at diagnosis.
methodsThe authors conducted a cross-sectional study at a São Paulo tertiary hospital. Patients were divided into 'symptomatic' and 'mammographic' detection groups. Bivariate analyses by detection method and clinical stage compared groups' profiles in terms of sociodemographic and clinical characteristics. Poisson regression analyses assessed sociodemographic and molecular subtypes´ influence on "mammographic detection" prevalence and "advanced-stage BC", reporting prevalence ratios and 95 % Confidence Intervals.
resultsThe authors studied 1,536 BC patients admitted from January 2016 to December 2017. The "mammographic detection" group had a higher proportion of patients aged 50‒69 years (62.9 % vs. 44.1 %), white race (63.3 % vs. 51.6 %), Catholic religion (58.2 % vs. 51.1 %), and Luminal A subtype (25.2 % vs. 13.2 %) compared to the "symptomatic detection" group. Patients with early-stage disease were more likely to have higher education levels (8.1 % vs. 5.5 %) and be married (39.8 % vs. 46.6 %) compared to those with advanced-stage. Molecular subtypes were significantly associated with the detection method and stage. The prevalence of advanced-stage disease in "mammographic" (n=313) and "symptomatic" (n=1191) groups was 18.5 % and 55 %, respectively . Mammographic detection significantly reduced advanced-stage BC prevalence (PR = 0.40, 95 % CI 0.31‒0.51).
conclusionMammographic detection reduces advanced-stage breast cancer prevalence in Brazil, emphasizing the importance of regular screenings, especially among at-risk sociodemographic groups. Enhancing mammographic screening accessibility, lowering the starting age to 40, and extending coverage to include annual mammograms can significantly lower breast cancer mortality in Brazil, benefiting public health and patient outcomes.
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