Evidence map›Paper›PMID 39413128›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Gut-to-brain regulation of

Jiangtian Chen, Marcela Nouzová, Fernando G Noriega, Marc Tatar

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Gut-brain communication in Drosophila melanogaster.Current opinion in neurobiology · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Gut-to-brain regulation ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jiangtian ChenDepartment of Ecology, Evolution and Organismal Biology, Brown University, Providence, RI 02912.ORCID 0000-0002-7226-1678
Marcela NouzováInstitute of Parasitology, Laboratory of Molecular Biology and Physiology of Mosquitoes, Biology Centre Czech Academy of Sciences, České Budějovice 37005, Czech Republic.ORCID 0000-0002-4562-1383
Fernando G NoriegaDepartment of Biological Sciences and Biomolecular Sciences Institute, Florida International University, Miami, FL 33199.ORCID 0000-0001-8628-5374
Marc TatarDepartment of Ecology, Evolution and Organismal Biology, Brown University, Providence, RI 02912.ORCID 0000-0003-3232-6884

Funding

FUNCTIONS AND INTERACTIONS DFOXO IN DROSOPHILA AGINGR37AG024360 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2011 to 2020
$4.5M
Aging regulation by non-autonomous signaling from Drosophila gut enteroendocrine cellsR01AG059563 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2018 to 2022
$1.9M
Functions and Interactions dFOXO in Drosopila AgingR01AG024360 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2004 to 2010
$1.7M
How can mosquitoes develop and reproduce in the complete absence of juvenile hormone?R21AI167849 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI FERNANDEZ-LIMA, FRANCISCO · 2022 to 2023
$369k
Czech Science Foundation 22-21244SHHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI167849HHS | NIH | National Institute on Aging (NIA) AG024360HHS | NIH | National Institute on Aging (NIA) AG059563NIAID NIH HHS R21 AI167849NIA NIH HHS R01 AG024360NIA NIH HHS R01 AG059563NIA NIH HHS R37 AG024360
6 · The paper itself

Abstract

Dietary restriction (DR) slows aging in many animals, while in some cases, the sensory signals from diet alone are sufficient to retard or accelerate lifespan. The digestive tract is a candidate location to sense nutrients, where neuropeptides secreted by enteroendocrine cells (EEC) produce systemic signals in response to food. Here, we measure how

Indexed as

Brain-Gut AxisDrosophila ProteinsInsulinJuvenile HormonesNeuropeptidesAgingAnimalsBrainDrosophila melanogasterEnteroendocrine CellsFemaleLongevityMaleNeuronsDrosophila ProteinsInsulinJuvenile Hormonesneuropeptide F, DrosophilaNeuropeptidesagingincretininsulininterorgan communicationjuvenile hormone

Identifiers

PMID39413128
PMCPMC11513968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.