Evidence map›Paper›PMID 39412946›Full record

ArticleThe Journal of dermatology2024

More than one shade of pink as a marker of early amelanotic/hypomelanotic melanoma.

M A Pizzichetta, P Corsetti, I Stanganelli, G Ghigliotti, S Cavicchini, V De Giorgi, R Bono, S Astorino, S Ribero, G Argenziano and 3 more

Abstract read
In one paragraph

Article in The Journal of dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

M A PizzichettaDepartment of Dermatology, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0002-4201-8490
P CorsettiDepartment of Medical Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
I StanganelliSkin Cancer Unit, Istituto Tumori Romagna (IRST), Meldola, Italy.
G GhigliottiPrivate Dermatologist, Genova, Italy.
S CavicchiniPrivate Dermatologist, Milan, Italy.
V De GiorgiDepartment of Dermatology, University of Florence, Florence, Italy.
R BonoPrivate Dermatologist, Roma, Italy.
S AstorinoDivision of Dermatology, Celio Hospital, Rome, Italy.
S RiberoDepartment Medical Sciences, Dermatologic Clinic, University of Torino, Turin, Italy.ORCID https://orcid.org/0000-0002-0098-1406
G ArgenzianoDermatology Unit, Second University of Naples, Naples, Italy.
AlaibacDepartment of Dermatology, University of Padova, Padova, Italy.
J PoleselCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Italian Melanoma Intergroup (IMI) and the Società Italiana di Dermatologia Chirurgica, Oncologica, Correttiva ed Estetica (SIDCO)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amelanotic/hypomelanotic melanoma (AHM) may be difficult to diagnose because of a lack of pigmentation. To evaluate whether dermoscopy can be useful for the diagnosis of early AHM, 133 digital dermoscopic images of lesions histopathologically diagnosed as amelanotic/hypomelanotic superficial spreading melanoma with ≤1 mm thickness (AHSSMs) (n = 27), amelanotic/hypomelanotic non-melanocytic lesions (AHNMLs) (e.g., seborrhoeic keratosis and basal cell carcinoma) (n = 79), and amelanotic/hypomelanotic benign melanocytic lesions (AHBMLs) (e.g., compound and dermal nevi) (n = 27), were dermoscopically assessed by three blinded dermatologists. Using multivariate analysis, we found a significantly increased risk of diagnosing AHSSM versus AHNML and AHBML when the lesion was characterized by the presence of more than one shade of pink (odds ratio [OR] 37.11), irregular dots/globules (OR 23.73), asymmetric pigmentation (OR 8.85), and structureless pattern (OR 7.33). In conclusion, dermoscopy may improve early AHM detection, discriminating AHSSM from amelanotic/hypomelanotic non melanoma lesions.

Indexed as

DermoscopyMelanoma, AmelanoticSkin NeoplasmsAdultAgedAged, 80 and overBasal Cell CarcinomaDiagnosis, DifferentialFemaleHumansMaleMelanomaMiddle AgedRetrospective StudiesSkinamelanotic melanomabenign melanocytic lesionnon‐melanocytic lesion

Identifiers

PMID39412946
PMCPMC11483925

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.