Evidence map›Paper›PMID 39412540›Full record

ArticleArchives of women's mental health2025

First episode depression during the perinatal period is associated with atopic diseases and persistently increased eosinophil and basophil levels.

En-Young N Wagner, Eva Maria Pichler, Mario Müller, Andrea Eisenhut, Ana Buadze, Yanhua Xu, Erich Seifritz, Marie-Pierre F Strippoli, Enrique Castelao, Setareh Ranjbar and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of women's mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

En-Young N WagnerDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Haldenbachstrasse 16/18, CH-8091, Zurich, Switzerland. en-young.wagner@uzh.ch.
Eva Maria PichlerDepartment of Psychiatry and Psychotherapy, Psychiatric Services Aargau, Windisch, Switzerland.
Mario MüllerDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.
Andrea EisenhutDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.
Ana BuadzeDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.
Yanhua XuDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.
Erich SeifritzDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.
Marie-Pierre F StrippoliDepartment of Psychiatry, Psychiatric Epidemiology and Psychopathology Research Center, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland.
Enrique CastelaoDepartment of Psychiatry, Psychiatric Epidemiology and Psychopathology Research Center, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland.
Setareh RanjbarDepartment of Psychiatry, Psychiatric Epidemiology and Psychopathology Research Center, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland.
Jennifer GlausDepartment of Psychiatry, Service of Child and Adolescent Psychiatry, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Caroline VandeleurDepartment of Psychiatry, Psychiatric Epidemiology and Psychopathology Research Center, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland.
Martin PreisigDepartment of Psychiatry, Psychiatric Epidemiology and Psychopathology Research Center, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland.
Roland von KänelDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Haldenbachstrasse 16/18, CH-8091, Zurich, Switzerland.
Vladeta Ajdacic-GrossDepartment of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, University of Zurich, Zurich, Switzerland.

Funding

Faculty of Biology and Medicine of the University of Lausanne Faculty of Biology and Medicine of the University of LausanneGlaxoSmithKline GlaxoSmithKlineSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 3200B0-105993, 3200B0-118308, 33CSCO-122661, 33CS30-139468, 33CS30-148401, 33CS30_177535 and 3247730_204523
6 · The paper itself

Abstract

purposeA previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND).

methodsWe examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus.

resultsNewly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils.

conclusionThe results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy.

Indexed as

AsthmaBasophilsDepressionEosinophilsHypersensitivityPregnancy ComplicationsAdultFemaleHumansPregnancyYoung AdultAtopyBasophilsDepressionEosinophilsPerinatal

Identifiers

PMID39412540
PMCPMC12092543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.