Evidence map›Paper›PMID 39412530›Full record

ArticleWorld journal of urology2024

Second-generation MOSES 2.0 versus MOSES 1.0 pulse-modulation technologies for holmium laser enucleation of the prostate (HoLEP).

Hazem Elmansy, Ryan Boudreau, Amr Hodhod, Saud Alhelal, Husain Alaradi, Khaled Alotaibi, Ruba Abdul Hadi, Oksana Blahitko, Ryan Kelly, Ahmed S Zakaria

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hazem ElmansyUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada. hazem.mansy@rocketmail.com.
Ryan BoudreauUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Amr HodhodUrology Department, King Abdulaziz Medical City, National Guard Hospitals Affairs, Riyadh, Saudi Arabia.
Saud AlhelalUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Husain AlaradiUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Khaled AlotaibiUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Ruba Abdul HadiUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Oksana BlahitkoUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Ryan KellyUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.
Ahmed S ZakariaUrology Department, Northern Ontario School of Medicine, Thunder Bay Regional Health Sciences Centre, 146 Court Street South Thunder Bay, Thunder Bay, ON, P7B 2X6, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectiveTo report our initial experience with enhanced MOSES 2.0 technology in patients who underwent holmium laser enucleation of the prostate (HoLEP) for the treatment of benign prostatic hyperplasia (BPH), in comparison to those who underwent HoLEP with MOSES 1.0 technology at our institution.

methodsWe retrospectively reviewed data of patients who underwent HoLEP using MOSES 1.0 or MOSES 2.0 pulse-modulation technology from December 2020 to September 2023. Preoperative and intraoperative parameters, postoperative outcomes, as well as perioperative complications were collected and analyzed.

resultsA total of 196 patients were included in the study. Among them, 146 patients underwent MOSES 1.0 HoLEP, while 50 had MOSES 2.0 HoLEP. No statistically significant differences in preoperative characteristics were observed between the two groups. The median prostate volume for the MOSES 1.0 and MOSES 2.0 HoLEP groups was 109 cc and 117.5 cc, respectively. Patients in the MOSES 2.0 group had a shorter median enucleation time (52.5 vs. 42.5 min, p < 0.001) and hemostasis time (8 vs. 6 min, p = 0.002), along with lower laser energy usage (101 vs. 86.4 kJ, p = 0.012), when compared to those in the MOSES 1.0 cohort. Postoperative outcomes, including IPSS, QoL, Qmax, and PVR, were comparable between the two groups at 1, 3, and 6 months postoperative. The incidence of hospital readmission (p = 0.42), as well as one-month postoperative urge urinary incontinence (p = 0.2) and stress urinary incontinence (p = 0.13) were also comparable between the cohorts.

conclusionsHoLEP with second-generation MOSES 2.0 technology is a safe and effective treatment option for BPH. It offers notable improvements, including reduced enucleation and hemostasis times, while using less energy when compared to MOSES 1.0.

Indexed as

Lasers, Solid-StateLaser TherapyProstatectomyProstatic HyperplasiaAgedHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeBenign prostatic hyperplasiaLaser

Identifiers

PMID39412530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.