Evidence map›Paper›PMID 39412495›Full record

Trial reportJournal of the National Cancer Institute2025

Reducing learning and psychosocial disparities in Latino children with cancer: a randomized intervention trial.

Sunita K Patel, Seong-Hyeon Kim, Kathleen Ingman, Van Huynh, Heather Huszti, Kimberly Kayser, Grace Mucci, Melissa Balderrama, Laura Bava, Abigail Onderwyzer Gold and 8 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the National Cancer Institute, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03178617 (Improving Learning and School Functioning in Latino Children With Cancer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03178617 naactive not recruitingnot on this map

Improving Learning and School Functioning in Latino Children With Cancer

TypeinterventionalSponsorCity of Hope Medical CenterRan2017 to 2026Enrolled214ConditionsAcute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma, Acute LeukemiaArmsEducational Intervention, Quality-of-Life Assessment, Questionnaire Administration
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sunita K PatelDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.ORCID 0000-0002-9023-8391
Seong-Hyeon KimDepartment of Clinical Psychology, School of Psychology and Marriage and Family Therapy, Fuller Theological Seminary, Pasadena, CA 91182, United States.
Kathleen IngmanDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States.ORCID 0000-0002-7823-0135
Van HuynhDivision of Pediatric Oncology, University of California Irvine College of Medicine, Irvine, CA 92697, United States.
Heather HusztiDepartment of Pediatric Psychology, Children's Hospital Orange County, Orange, CA 92868, United States.ORCID 0000-0003-2277-1714
Kimberly KayserDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States.
Grace MucciDepartment of Pediatric Psychology, Children's Hospital Orange County, Orange, CA 92868, United States.ORCID 0000-0002-9993-959X
Melissa BalderramaDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States.
Laura BavaCancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA 90027, United States.
Abigail Onderwyzer GoldDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.
Alicia WuthDepartment of Pediatric Psychology, Children's Hospital Orange County, Orange, CA 92868, United States.
Nicole DelgadoDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.ORCID 0009-0006-8473-5494
Alysia BosworthDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.
Emily NishimuraDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.
Harneet HaraDivision of Oncology, Hyundai Cancer Institute, Children's Hospital Orange County, Orange, CA 92868, United States.
Anna PawlowskaDepartment of Pediatrics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.ORCID 0000-0001-9466-6396
Lisa MuellerDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Kaiser Permanente Medical Center, Los Angeles, CA 90027, United States.
F Lennie WongDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.ORCID 0000-0002-4333-5017

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
American Cancer SocietyAmerican Cancer Society 17-023-01-CPPBCity of Hope Center for InformaticsNCI NIH HHS P30 CA033572NIH HHSNIH HHS P30CA33572
6 · The paper itself

Abstract

backgroundWe developed a high-intensity parenting intervention program (HIP) to help parents support the academic success of childhood cancer survivors (CCSs), who often face post-treatment challenges affecting their school-related functioning. This randomized controlled trial (NCT03178617) evaluated HIP's efficacy compared with lower-intensity, single-session, treatment-as-usual services (lower-intensity program [LIP]) in Latino families. Primary outcomes were parenting efficacy and CCSs' school functioning; secondary outcomes included parenting knowledge and measures of CCSs' academic performance, attention, and functioning outside of school.

methodsIn total, 106 Latino survivors of childhood leukemia and lymphoblastic lymphoma (aged 6-12 years) and their parents were randomly assigned to HIP (n = 54) or LIP (n = 52). Linear mixed-effects models evaluated group differences across baseline, 6-month (T2), and 12-month (T3) assessments.

resultsParenting efficacy and knowledge improved significantly in the HIP arm, resulting in higher scores vs LIP at T2 and T3 (P ≤ .01). No significant between-group differences were found in child school functioning; however, HIP children showed significantly better social functioning and performance on 1 measure of attention (CPT-3 commissions) at T3 (P < .05). Although HIP adherence challenges were observed, with only 33 (61%) completing the intervention, exploratory analyses suggest that benefits were most evident among those who were fully engaged. Satisfaction and perceived benefit were greater for HIP vs LIP at both time points (P < .05).

conclusionsOur results suggest the potential value of parent-directed behavioral interventions such as HIP for CCSs and their families. Further studies are needed to address participation barriers and enhance engagement to maximize and sustain benefits.

Indexed as

Cancer SurvivorsHispanic or LatinoLearningNeoplasmsParentingAttentionChildCognitionCognitive DysfunctionCognitive RemediationEducational MeasurementEducation, NonprofessionalExecutive FunctionFemaleHumansMale

Identifiers

PMID39412495
PMCPMC11884853

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.