Evidence map›Paper›PMID 39412096›Full record

ReviewThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2024

The Double-Edged Sword Property of Mesenchymal Stem Cell-Derived Exosomal microRNAs in Colorectal Cancer.

Hongliang Yao, Caihua Sun, Chengjun Wang, Jipan Liu, Yun Li, Li Li, Bin Zhao, Jia Liu

Abstract readReview
In one paragraph

Review in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prognostic Value of Long Non-Coding RNAs GUSB Pseudogene 11 in Colorectal Cancer and Its Regulatory Effect on Tumor Progression.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongliang YaoThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Caihua SunThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Chengjun WangThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Jipan LiuThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Yun LiThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Li LiThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Bin ZhaoThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.
Jia LiuThe Second Department of General Surgery, Hengshui People's Hospital, Hengshui, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs)-based therapies are promising therapeutic strategies for cancer treatment, because of their strong immunomodulatory and tissue regeneration abilities. In case of colorectal cancer (CRC), MSCs indicate a double-edged sword activity. Some reports declared the inhibitory effects of MSCs on the proliferation, migration, and infiltration of cancer cells to suppress the CRC initiation and development, whereas others showed the tumor-promoter impacts of MSCs on the progression of CRC. Recent investigations have revealed that exosomal microRNAs (Exo-miRs) derived from MSCs (MSCs-Exo-miRs) are attributed to such paradoxical effect. Thus, the current review aimed to seek the role of MSCs-Exo-miRs in CRC progression and their therapeutic potential for the CRC treatment.

Indexed as

Colorectal NeoplasmsExosomesMesenchymal Stem CellsMicroRNAsCell MovementCell ProliferationDisease ProgressionHumansMicroRNAs

Identifiers

PMID39412096
PMCPMC11465186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.