Evidence map›Paper›PMID 39411994›Full record

Observational studyEuropean journal of anaesthesiology2025

A comparison between invasive and noninvasive measurement of the Hypotension Prediction Index: A post hoc analysis of a prospective cohort study.

Santino R Rellum, Eline Kho, Jimmy Schenk, Björn J P van der Ster, Alexander P J Vlaar, Denise P Veelo

Registry-linked trialAbstract readObservational StudyComparative Study
In one paragraph

Observational study in European journal of anaesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03795831 (Validation Study in Patients of a Non-invasive Blood Pressure Monitor for Perioperative Use), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03795831 unknown statusnot on this map

Validation Study in Patients of a Non-invasive Blood Pressure Monitor for Perioperative Use

Typeobservational_patient_registrySponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2017 to 2019Enrolled100ConditionsIntraoperative HypotensionArmsClearSight feasibility testing
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Santino R RellumFrom the Department of Anaesthesiology (SRR, EK, JS, BJPvdS, DPV), Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences (SRR, EK, JS, APJV) and Department of Epidemiology and Data Science, Amsterdam UMC, University of Amsterdam, Amsterdam Public Health, Amsterdam, the Netherlands (JS).
Eline Kho
Jimmy Schenk
Björn J P van der Ster
Alexander P J Vlaar
Denise P Veelo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical trials and validation studies demonstrate promising hypotension prediction capability by the Hypotension Prediction Index (HPI). Most studies that evaluate HPI derive it from invasive blood pressure readings, but a direct comparison with the noninvasive alternative remains undetermined. Such a comparison could provide valuable insights for clinicians in deciding between invasive and noninvasive monitoring strategies.

objectivesEvaluating predictive differences between HPI when obtained through noninvasive versus invasive blood pressure monitoring.

designPost hoc analysis of a prospective observational study conducted between 2018 and 2020.

settingSingle-centre study conducted in an academic hospital in the Netherlands. PATIENTS: Adult noncardiac surgery patients scheduled for over 2 h long elective procedures. After obtaining informed consent, 91 out of the 105 patients had sufficient data for analysis.

main outcome measuresThe primary outcome was the difference in area under the receiver-operating characteristics (ROC) curve (AUC) obtained for HPI predictions between the two datasets. Additionally, difference in time-to-event estimations were calculated.

resultsAUC (95% confidence interval (CI)) results revealed a nonsignificant difference between invasive and noninvasive HPI, with areas of 94.2% (90.5 to 96.8) and 95.3% (90.4 to 98.2), respectively with an estimated difference of 1.1 (-3.9 to 6.1)%; P  = 0.673. However, noninvasive HPI demonstrated significantly longer time-to-event estimations for higher HPI values.

conclusionNoninvasive HPI is reliably accessible to clinicians during noncardiac surgery, showing comparable accuracy in HPI probabilities and the potential for additional response time.

trial registrationClinicaltrials.gov (NCT03795831) https://clinicaltrials.gov/study/NCT03795831.

Indexed as

HypotensionAdultAgedBlood PressureBlood Pressure DeterminationCohort StudiesFemaleHumansMaleMiddle AgedMonitoring, IntraoperativeNetherlandsPredictive Value of TestsProspective Studies

Identifiers

PMID39411994
PMCPMC11676597

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.