Evidence map›Paper›PMID 39411711›Full record

ArticleFrontiers in immunology2024

Prognostic significance of fludeoxyglucose positron emission tomography delta radiomics following bridging therapy in patients with large B-cell lymphoma undergoing CAR T-cell therapy.

Colton Ladbury, Claire Hao, William Tyler Watkins, Sagus Sampath, Jeffrey Wong, Arya Amini, Karen Sokolov, Jekwon Yeh, Karine A Al Feghali, Dorine de Jong and 8 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Summary Report of the SNMMI AI Task Force Radiomics Challenge 2024.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Colton LadburyDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Claire HaoDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
William Tyler WatkinsDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Sagus SampathDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Jeffrey WongDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Arya AminiDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Karen SokolovDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Jekwon YehDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.
Karine A Al FeghaliRefleXion Medical, Inc., Hayward, CA, United States.
Dorine de JongRefleXion Medical, Inc., Hayward, CA, United States.
Arjun ManiyedathRefleXion Medical, Inc., Hayward, CA, United States.
Shervin ShirvaniRefleXion Medical, Inc., Hayward, CA, United States.
Liana NikolaenkoDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.
Matthew MeiDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.
Alex HerreraDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.
Leslie PopplewellDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.
Lihua Elizabeth BuddeDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.
Savita DandapaniDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose/objectives: Bridging radiation therapy (bRT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell therapy for large B-cell lymphoma (LBCL). It is unknown how the extent of cytoreduction during bRT impacts outcomes. Materials/methods: We retrospectively reviewed patients with LBCL treated with bRT followed by CAR T-cell therapy. Metabolic tumor volume (MTV), maximum standardized uptake value (SUV Results: Thirty-three sites across 23 patients with LBCL were irradiated. All metabolically active disease was treated in 10 patients. Following bRT, median overall decreases (including unirradiated sites) in MTV, SUV Conclusion: bRT led to substantial reductions in MTV, SUV

Indexed as

Fluorodeoxyglucose F18Immunotherapy, AdoptiveLymphoma, Large B-Cell, DiffusePositron-Emission TomographyAdultAgedFemaleHumansMaleMiddle AgedPrognosisRadiomicsRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18bridging radiationchimeric antigen receptor T-cell (CAR T)delta radiomicslarge B-cell lymphoma (LBCL)positron emission tomography

Identifiers

PMID39411711
PMCPMC11473334

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.