ArticleCureus2024
Clinical Impact of Weight Loss During Hospitalization on Prognosis After Pancreatic Surgery.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of Preoperative Weight Loss on Prognosis in Patients with Pancreatic Cancer.Biomedicines · 2025Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose This study aimed to elucidate the relationship between early-stage weight loss (WL) during hospitalization after pancreatic surgery and prognosis and investigate risk factors affecting WL. Methods We included 68 patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) who underwent radical surgery. The %WL value was calculated based on the percentage of body weight at discharge compared with the body weight at admission. High WL was defined as %WL >10%. We initially evaluated the association between %WL and postoperative survival using the Kaplan-Meier method. Subsequently, we analyzed the factors affecting %WL using a logistic regression model. Results In terms of overall survival (OS), the high %WL group exhibited a significantly worse prognosis than the low %WL group (p=0.043). Univariate analysis revealed a hazard ratio of 2.244 (95% confidence interval (CI), 1.006-5.006; p=0.048) for high %WL in relation to overall survival. Multivariate analysis identified an operative time >450 min (odds ratio, 17.8; 95% confidence interval, 1.01-312.42; p=0.049) and postoperative complications (odds ratio, 12.1; 95% confidence interval, 2.01-72.79; p<0.01) as independent risk factors for high %WL. Conclusion Preventing high %WL by streamlining surgical procedures, minimizing postoperative complications, and implementing medical nutritional therapy (MNT) is imperative to improve the prognosis of patients with PDAC.
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