Evidence map›Paper›PMID 39411456›Full record

ArticleHealth affairs scholar2024

Biopharmaceutical pipeline funded by venture capital firms, 2014 to 2024.

So-Yeon Kang, Mingqian Liu, Jeromie Ballreich, Ravi Gupta, Gerard Anderson

Abstract read
In one paragraph

Article in Health affairs scholar, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

So-Yeon KangDepartment of Health Management and Policy, Georgetown University School of Health, Washington, DC 20007, United States.ORCID https://orcid.org/0000-0002-6304-9368
Mingqian LiuData Science and Analytics Program, Graduate School of Arts & Sciences, Georgetown University, Washington, DC 20057, United States.ORCID https://orcid.org/0009-0006-7667-3297
Jeromie BallreichDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Ravi GuptaDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.ORCID https://orcid.org/0000-0001-5902-6414
Gerard AndersonDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.ORCID https://orcid.org/0000-0003-1845-1523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venture capital (VC) firms fund biopharmaceutical research and development (R&D) while incurring substantial financial risk. VC firms seek to invest in clinical areas with the greatest potential for financial return. Using a combination of data for clinical trials and VC investment deals between January 2014 and March 2024, we found that approximately 75% of VC investments were allocated to clinical trials studying small-molecule drugs compared to biologics or gene therapies, without substantial changes over the study period. Most of VC firms' investment in biopharmaceutical R&D was concentrated in phase 1 and phase 2 clinical trials. This trend has increased in recent years, with phase 1 trials accounting for nearly half of total deals and capital investments in 2023. VC investments were concentrated in several therapeutic areas, including cancer.

Indexed as

biopharmaceutical industrydrug developmentinvestment in research and developmentprescription drug policy

Identifiers

PMID39411456
PMCPMC11476778

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.