Evidence map›Paper›PMID 39411431›Full record

ArticleFrontiers in microbiology2024

Emergence and evolution of mosaic

Jesse C Thomas Iv, John C Cartee, Katherine Hebrank, Sancta B St Cyr, Karen Schlanger, Brian H Raphael, Ellen N Kersh, Sandeep J Joseph

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesse C Thomas IvDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
John C CarteeDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Katherine HebrankOak Ridge Institute for Science and Education Research Participation and Fellowship Program, Oak Ridge, TN, United States.
Sancta B St CyrDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Karen SchlangerDivision of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Brian H RaphaelDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Ellen N KershDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Sandeep J JosephDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: In this study, we assessed phylogenomic relatedness and antimicrobial resistance (AMR) determinant profiles of these three isolates with high-level ceftriaxone MICs among a global collection of 2,104 genomes belonging to the MLST-1901 core genome cluster group 31, which includes strains separated by a locus threshold of 200 or fewer differences (Ng_cgc_200). Recombination events in and around the Results: The global population structure of MLST-1901 core genogroup falls into 4 major lineages. Isolates GCWGS-10723, F92, and H22-722 clustered within Lineage 1, which was dominated by non-mosaic penA-5 alleles. These three isolates formed a clade within Lineage 1 that consisted of isolates from North America and southeast Asia. Discussions: Our study suggests that there are multiple evolutionary pathways that could generate concerning mosaic

Indexed as

antibiotic resistanceceftriaxone resistancehomologous recombinationNeisseria gonorrhoeae (Ng)phylogenomics

Identifiers

PMID39411431
PMCPMC11473337

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.