Evidence map›Paper›PMID 39411423›Full record

ArticleAmerican journal of ophthalmology case reports2024

Multifocal vitelliform lesions associated with mitochondrial retinopathy.

Maurizio Battaglia Parodi, Alessio Antropoli, Lorenzo Bianco, Alessandro Arrigo, Sebastiano Del Fabbro, Paola Carrera, Ivana Spiga, Alessia Catania, Costanza Lamperti, Francesco Bandello and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maurizio Battaglia ParodiOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alessio AntropoliOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Lorenzo BiancoOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alessandro ArrigoOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Sebastiano Del FabbroOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Paola CarreraUnit of Genomics for Human Disease Diagnosis, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ivana SpigaLaboratory of Clinical Molecular Genetics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alessia CataniaMedical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20126, Milan, Italy.
Costanza LampertiMedical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20126, Milan, Italy.
Francesco BandelloOphthalmology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ahmad MansourOphthalmology Department, American University of Beirut, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report a case of multifocal vitelliform lesions in a patient affected by metabolic encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) with the m.3243A>G variant. Observations: A 37-year-old woman affected by MELAS was referred to our center for progressive vision deterioration. On fundus examination, she presented bilateral macular atrophy associated in the left eye with neurosensory detachment, along with several bilateral vitelliform lesions close to the vascular arcades. We describe the dynamic evolution of the vitelliform lesions, which could either enlarge and coalesce or undergo atrophic evolution. Conclusions: Mitochondrial retinopathy due to the m.3243A>G variant can be associated with multifocal vitelliform lesions.

Indexed as

Autofluorescence imagingMitochondrial retinopathyOCT

Identifiers

PMID39411423
PMCPMC11474458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.