Evidence map›Paper›PMID 39411215›Full record

ArticleOpen forum infectious diseases2024

Clinical Manifestations and Outcomes in Adults Hospitalized With Respiratory Syncytial Virus and Influenza a/B: A Multicenter Observational Cohort Study.

Clara Lundetoft Clausen, Amanda Marie Egeskov-Cavling, Noor Hayder, Adin Sejdic, Casper Roed, Jon Gitz Holler, Lene Nielsen, Mads Frederik Eiberg, Omid Rezahosseini, Christian Østergaard and 4 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Characteristics and outcomes of adult patients hospitalised with RSV infection, influenza or COVID-19 in Belgium, winter seasons 2023/24 and 2024/25.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  5. Long-term Clinical Outcomes After Hospitalization for Acute Respiratory Illness Due to Respiratory Syncytial Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Characteristics and outcomes of hospitalized adult patients with respiratory syncytial virus infection in different age groups.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Clara Lundetoft ClausenCenter of Research and Disruption of Infectious Diseases (CREDID), Department of Infectious Diseases, Amager and Hvidovre Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1745-2623
Amanda Marie Egeskov-CavlingDepartment of Clinical Research, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.ORCID https://orcid.org/0009-0000-1263-2759
Noor HayderCenter of Research and Disruption of Infectious Diseases (CREDID), Department of Infectious Diseases, Amager and Hvidovre Hospital, Copenhagen, Denmark.
Adin SejdicDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Casper RoedDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Jon Gitz HollerDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Lene NielsenDepartment of Clinical Microbiology, Herlev and Gentofte Hospital, Copenhagen, Denmark.
Mads Frederik EibergDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Omid RezahosseiniDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.ORCID https://orcid.org/0000-0003-2198-1904
Christian ØstergaardDiagnostic Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark.
Zitta Barrella HarboeDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Thea K FischerDepartment of Clinical Research, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.
Thomas BenfieldCenter of Research and Disruption of Infectious Diseases (CREDID), Department of Infectious Diseases, Amager and Hvidovre Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-0698-9385
Birgitte LindegaardDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital, North Zealand Hospital, Hilleroed, Denmark.ORCID https://orcid.org/0000-0002-5236-8427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory syncytial virus (RSV) and influenza cause significant health challenges, particularly for individuals with comorbid conditions and older adults. However, information on the clinical manifestations and outcomes of adults hospitalized with RSV in Europe remains limited. Methods: This multicenter observational cohort study of adults hospitalized with RSV or influenza A or B from March 2016 to April 2020 investigated the clinical manifestations, mortality risk factors, and association with 90-day mortality rates by logistic regression analysis after adjustment for covariates. Results: Of 988 patients hospitalized with either virus, 353 had RSV, 347 had influenza A, and 288 had influenza B infection. Patients with RSV, compared with those with influenza A or B, were more likely to have comorbid conditions (83% for RSV vs 72% for influenza A [ Conclusions: Older adults hospitalized with RSV infections are at a higher risk of dying within 90 days of hospitalization than patients admitted with influenza B but at a similar risk as those admitted with influenza A, emphasizing the detrimental effects and severity of older patients being infected with RSV. Our findings underscore the need for strategic testing and vaccination approaches to mitigate the impact of RSV among older adults.

Indexed as

adultsclinical epidemiologymortalityrespiratory infectionsrespiratory syncytial virus

Identifiers

PMID39411215
PMCPMC11474596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.