Evidence map›Paper›PMID 39410948›Full record

ReviewHealth science reports2024

Treatment strategies for erosive genital lichen planus: A systematic review of therapeutic modalities and emerging breakthroughs.

Borna Safari-Kish, Matin Bidares, Shirin Zaresharifi, Hesam Malekzadeh-Shoushtari, Mahsa Aziz, Mahsa Salehi, Khatere Zahedi

Abstract readReview
In one paragraph

Review in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Atypical Orogenital Lichen Planus in a Young Male: A Case Report.Clinical medicine insights. Case reports · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Borna Safari-KishClinical Research Development Center, Najafabad Branch Islamic Azad University Najafabad Iran.ORCID 0000-0002-5392-275X
Matin BidaresClinical Research Development Center, Najafabad Branch Islamic Azad University Najafabad Iran.
Shirin ZaresharifiSkin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID 0000-0003-4002-6953
Hesam Malekzadeh-ShoushtariSchool of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.
Mahsa AzizClinical Research Development Center, Najafabad Branch Islamic Azad University Najafabad Iran.
Mahsa SalehiDepartment of Pathology, School of Medicine Mazandaran University of Medical Sciences Mazandaran Iran.
Khatere ZahediSkin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Erosive genital lichen planus (EGLP) is a severe form of lichen planus characterized by painful erosions in the genital area, leading to significant distress and complications. This review aims to provide a thorough examination of EGLP, focusing on its clinical manifestations, diagnostic challenges, and various treatment strategies, with an emphasis on patient-centered care. Methods: Adhering to PRISMA guidelines, we conducted a systematic review of 26 studies that explored dermatological treatments for EGLP. Our literature search was comprehensive, covering PubMed, Scopus, and Web of Science. Data were extracted systematically using established tools to ensure a robust analysis of the treatment modalities. Results: EGLP presents with a range of symptoms, including severe pain, itching, and sexual dysfunction. Treatment options include topical corticosteroids, systemic medications, and surgical interventions. Despite the availability of various therapies, many cases are refractory to treatment, resulting in chronic symptoms and reduced quality of life. Emerging therapies show promise but are not yet established as standard practice. Conclusion: Management of EGLP requires a tailored, multidimensional approach. While topical corticosteroids remain essential, the development of new therapies offers hope for improved outcomes. A patient-centered approach is vital to address both the physical and psychosocial impacts of EGLP. Continued research is necessary to refine treatment protocols and enhance patient care.

Indexed as

EGLPErosive genital lichen planuslichen planustreatment

Identifiers

PMID39410948
PMCPMC11473378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.