Evidence map›Paper›PMID 39410930›Full record

ArticleFrontiers in nutrition2024

Changes in haptoglobin genotype-based gene expressions upon the observance of dawn-to-dusk intermittent fasting: a prospective cohort study on overweight and obese individuals.

Mohamed I Madkour, Rasha E Hassan, Naglaa M Sherif, Samir Awadallah, Nada M Farahat, Dana N Abdelrahim, Fatima A AlHasan, Jalal Taneera, MoezAlIslam E Faris

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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mohamed I MadkourDepartment of Medical Laboratory Sciences, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Rasha E HassanBiochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.
Naglaa M SherifBiochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.
Samir AwadallahDepartment of Medical Laboratories, College of Allied Medical Sciences, Zarqa University, Zarqa, Jordan.
Nada M FarahatResearch Institute of Medical and Health Sciences (RIMHS), Center of Excellence for Public Health, University of Sharjah, Sharjah, United Arab Emirates.
Dana N AbdelrahimResearch Institute of Medical and Health Sciences (RIMHS), Center of Excellence for Public Health, University of Sharjah, Sharjah, United Arab Emirates.
Fatima A AlHasanDepartment of Medical Laboratory Medicine, King Fahd Hospital, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Jalal TaneeraCollege of Medicine, Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah, United Arab Emirates.
MoezAlIslam E FarisDepartment of Clinical Nutrition and Dietetics, Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Intermittent fasting (IF) has been reported to be involved in ameliorating oxidative stress and lessening the systemic-low grade inflammation that predisposes to chronic diseases. Gene polymorphism is currently a main determining factor for the metabolic responses to different dietary and lifestyle modifications. Methods: The current study was designed to explore the effect of observing four-week, dawn to dusk IF by participants with obesity on gene expression of the anti-inflammatory Results: The expressions of Conclusion: Participants with genotypes Hp2-1 and Hp2-2 revealed upregulation of the antioxidant genes in response to the metabolic stress induced by IF compared with Hp1-1, implying that Hp polymorphism plays a key role in shaping the body's response to dietary modifications such as fasting.

Indexed as

calorie restrictionGene polymorphisiminflammationnutritional genomicsoxidative stresstime-restricted eating

Identifiers

PMID39410930
PMCPMC11475474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.