Evidence map›Paper›PMID 39410773›Full record

ArticleActa radiologica (Stockholm, Sweden : 1987)2024

Assessment of pediatric breast ultrasound less is more: a practical imaging approach.

Elisabetta Giannotti, Rachel Sun, Nuala Healy, Fleur Kilburn-Toppin, Carmelo Sofia, Andrew Hs Lee, Maria Adele Marino

Abstract read
In one paragraph

Article in Acta radiologica (Stockholm, Sweden : 1987), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisabetta GiannottiCambridge Breast Unit, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.ORCID 0000-0001-6924-9822
Rachel SunNottingham Breast Institute, Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Nottingham, UK.
Nuala HealyCambridge Breast Unit, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Fleur Kilburn-ToppinCambridge Breast Unit, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Carmelo SofiaDepartment of Biomedical Sciences and Morphologic and Functional Imaging, Policlinico Universitario "G.Martino", University of Messina, Messina, Italy.
Andrew Hs LeeHistopathology Department, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK.ORCID 0000-0003-2496-4050
Maria Adele MarinoDepartment of Biomedical Sciences and Morphologic and Functional Imaging, Policlinico Universitario "G.Martino", University of Messina, Messina, Italy.ORCID 0000-0002-5614-2660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer in pediatric patients is rare, but ultrasound (US) is widely utilized for symptomatic cases. PURPOSE: To determine biopsy and cancer detection rates of pediatric patients and to assess if breast US can be omitted. MATERIAL AND

methodsA retrospective review of a 5-year period was conducted of single-center breast US performed in patients aged <19 years. Data regarding presentation, clinical opinion (P1-5 score), and US (U1-5 score) were collected. If biopsy or surgery was performed, pathology was reviewed (B1-5 score).

resultsIn total, 579 patients were included (19 boys, 560 girls; mean age=16.2±1.9 years; age range=0-18 years). Clinical examination was normal or benign (P1/P2) in all boys (100%) and 557/560 (99.5%) girls, and P3 in 3 (0.5%) girls. Of US, 52% demonstrated normal findings (U1) for both sexes (300/579); in the remaining cases, the most frequent findings were gynecomastia in 12/19 boys and well-defined breast masses in 208/560 girls. Of the 560 girls, 6 (1%) underwent US-guided biopsy, with final histology of fibroadenoma (B2) in all cases, while 27 (5%) had a surgical excision, with final histology of fibroadenoma (22/27, 81.5%), hamartoma (2/27, 7.4%), benign phyllodes tumor (2/27, 7.4%), and angiomyxoma skin lesion (1/27, 3.7%). No malignant lesions were diagnosed at the time of clinical referral or during the 18-month follow-up in patients with a well-defined mass on US.

conclusionBreast malignancy is extremely rare in pediatric population. US can be safely omitted if clinical examination is normal; this approach would have avoided breast US in 52% of patients in this study.

Indexed as

Breast NeoplasmsUltrasonography, MammaryAdolescentBreastChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesBreastbreast cancerpediatricultrasound

Identifiers

PMID39410773
PMCPMC11633068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.