Evidence map›Paper›PMID 39410745›Full record

ArticleJournal of surgical oncology2024

CT Imaging as a Single Modality for Clinical Staging of Gastric Cancer in Limited Resource Centers: A Retrospective Pilot Study.

Kyle D Klingbeil, Isabel K Eng, Priyanka Dube, Dustin L Dillon, Kirollos Bechay, Shawdi Manouchehr-Pour, Roshan Bastani, Karoly Viragh, Mariam R Thomas, Brian E Kadera

Abstract read
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In one paragraph

Article in Journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyle D KlingbeilDepartment of Surgery, Division of Surgical Oncology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-4359-5556
Isabel K EngDavid Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID http://orcid.org/0009-0009-1062-2245
Priyanka DubeDepartment of Radiology, UCLA-Olive View Medical Center, Sylmar, California, USA.ORCID https://orcid.org/0000-0002-5973-1014
Dustin L DillonDavid Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID http://orcid.org/0000-0002-9272-4481
Kirollos BechayDavid Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-8897-2431
Shawdi Manouchehr-PourDepartment of Radiology, UCLA-Olive View Medical Center, Sylmar, California, USA.ORCID https://orcid.org/0009-0009-1879-5677
Roshan BastaniUCLA Fielding School of Public Health, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-6594-9231
Karoly ViraghDepartment of Radiology, UCLA-Olive View Medical Center, Sylmar, California, USA.ORCID https://orcid.org/0000-0002-0139-2507
Mariam R ThomasDepartment of Radiology, UCLA-Olive View Medical Center, Sylmar, California, USA.ORCID https://orcid.org/0000-0002-3936-1108
Brian E KaderaDepartment of Surgery, Division of Surgical Oncology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-5133-8656

Funding

This study was supported by the Department of Surgery, UCLA Health and the Department of Surgery, Olive View Medical Center.
6 · The paper itself

Abstract

backgroundGastric cancer disproportionately impacts populations in resource-limited settings. Within a safety-net network, we assessed the utility of computed tomography (CT) as a single staging modality.

methodsWe utilized a clinical database of gastric cancer patients treated within the Los Angeles County safety-net hospital system from 2016 to 2023 in conjunction with retrospective imaging review by certified radiologists. We assessed agreement between clinical and pathological staging for patients who underwent curative gastrectomy using the Kappa coefficient.

resultsOf 107 patients with available CT imaging, 43.9% (n = 47) were staged with CT as a single modality. Most tumors displayed infiltrating (75%) or diffuse (28%) morphology, 41% displayed adequate gastric distention and regional lymphadenopathy was common (68%). Twenty-nine patients underwent curative gastrectomy. Overall agreement was minimal (κ = 0.29, 95% CI [0.071-0.51], p = 0.022), weak for T3/T4 tumors (κ = 0.50, 95% CI [0.17-0.82], p < 0.01), and weak for Hispanic/Latino patients (κ = 0.47, 95% CI [0.19-0.76], p < 0.01).

conclusionsThere was minimal agreement between clinical and pathologic staging when assessing clinical stage by CT imaging alone, suggesting that CT is not adequate as a single modality staging tool. While every effort should be made to obtain multimodal staging, larger studies are warranted to improve CT imaging protocols for staging in resource-limited settings.

Indexed as

Stomach NeoplasmsTomography, X-Ray ComputedAdultAgedAged, 80 and overFemaleGastrectomyHumansMaleMiddle AgedNeoplasm StagingPilot ProjectsRetrospective Studiescancer epidemiologycancer stagingcomputed tomographydisparitiesgastric adenocarcinomagastric cancerhealth disparitiesHispanic/Latinopublic healthsafety‐net hospital systems

Identifiers

PMID39410745
PMCPMC11849710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.