Evidence map›Paper›PMID 39410722›Full record

ArticleAging cell2025

The N6-methyladenosine landscape of ovarian development and aging highlights the regulation by RNA stability and chromatin state.

Xiujuan Hu, Jiafeng Lu, Chenyue Ding, Jincheng Li, Qinyan Zou, Wenjuan Xia, Chunfeng Qian, Hong Li, Boxian Huang

Abstract read
In one paragraph

Article in Aging cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Decreased FTO Expression Promotes Ovarian Granulosa Cells Aging.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  9. Article
  10. Article
  11. Unveiling the dynamics and therapeutic potential of mInternational journal of biological sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiujuan HuState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Jiafeng LuState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Chenyue DingState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Jincheng LiState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Qinyan ZouState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Wenjuan XiaState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Chunfeng QianState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Hong LiState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Boxian HuangState Key Laboratory of Reproductive Medicine and Offspring Health, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.ORCID 0000-0001-9913-9077

Funding

Jiangsu Province 333 Talent Grant 2022-3-2-155The National Natural Science Foundation of China 82071720The National Natural Science Foundation of China 92168104
6 · The paper itself

Abstract

The versatile epigenetic modification known as N6-methyladenosine (m

Indexed as

AdenosineAgingChromatinOvaryRNA StabilityAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsFemaleHumansMethyltransferasesMiceMice, KnockoutAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOChromatinMethyltransferasesN-methyladenosineautophagyendogenous retrovirusesFTOH3K9me3METTL16N6‐methyladenosineovarian agingSUV39H1

Identifiers

PMID39410722
PMCPMC11822672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.