Evidence map›Paper›PMID 39410659›Full record

ArticleACS infectious diseases2025

d-[5-

Cynthia M Co, Aditi Mulgaonkar, Ning Zhou, Tam P Nguyen, Shelby Harris, Amber Sherwood, Vicki Ea, Katie Rubitschung, Laila Castellino, Orhan K Öz and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Recent advances in [Nuclear medicine and biology · 2026
    Review
  2. Article
  3. Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cynthia M CoDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.ORCID 0000-0002-5779-5444
Aditi MulgaonkarDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.
Ning ZhouDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.ORCID 0000-0002-8967-3468
Tam P NguyenDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.
Shelby HarrisDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.
Amber SherwoodDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.ORCID 0000-0003-2211-8504
Vicki EaDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.
Katie RubitschungDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.
Laila CastellinoDivision of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UTSW, Dallas, Texas 75390, United States.
Orhan K ÖzDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.
Xiankai SunDepartment of Radiology, University of Texas Southwestern Medical Center (UTSW), Dallas, Texas 75390, United States.ORCID 0000-0002-5140-6110
Liping TangDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.ORCID 0000-0002-3393-7073

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
Interdisciplinary Training in Nanotechnology for Cardiovascular and Lung Diseases in North TexasT32HL134613 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG · 2017 to 2021
$1.1M
NCI NIH HHS P30 CA142543NHLBI NIH HHS T32 HL134613
6 · The paper itself

Abstract

Orthopedic implant infections (OIIs) present diagnostic and therapeutic challenges, owing to the lack of methods to distinguish between active infection and sterile inflammation. To address this unmet need, d-amino-acid-based radiotracers with unique metabolic profiles in microorganisms have emerged as a novel class of infection-specific imaging agents. Given the pivotal role of d-glutamine in bacterial biofilm formation and virulence, herein, we explored the potential of positron emission tomography (PET) imaging with d-[5-

Indexed as

BiofilmsGlutaminePositron-Emission TomographyProsthesis-Related InfectionsStaphylococcal InfectionsStaphylococcus aureusAnimalsAnti-Bacterial AgentsCarbon RadioisotopesDisease Models, AnimalFluorodeoxyglucose F18MaleRadiopharmaceuticalsRatsRats, Sprague-DawleyAnti-Bacterial AgentsCarbon RadioisotopesFluorodeoxyglucose F18GlutamineRadiopharmaceuticalsd-amino acidglutamineorthopedic implant infectionspositron emission tomographyStaphylococcus aureus

Identifiers

PMID39410659
PMCPMC12002399

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.