Evidence map›Paper›PMID 39410652›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Etiology, Clinical Profiles, and Outcomes of Acute Encephalitis Syndrome Cases Admitted to a Tertiary Care Center in Myanmar in 2023.

Aung Kyaw Kyaw, Ohnmar, Zin Nwe Win, Sai Kyaw Win, Zarni Myint Shwe, Kyaw Lwin Show, Nan Aye Thida Oo, Mya Thandar Win, Khin Zarchi Aung, Win Pa Pa Naing and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aung Kyaw KyawDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.ORCID 0000-0002-1384-8030
OhnmarDepartment of Neurology, University of Medicine 1, Yangon General Hospital, Ministry of Health, Yangon 11111, Myanmar.
Zin Nwe WinDepartment of Neurology, University of Medicine 1, Yangon General Hospital, Ministry of Health, Yangon 11111, Myanmar.
Sai Kyaw WinDepartment of Neurology, University of Medicine 1, Yangon General Hospital, Ministry of Health, Yangon 11111, Myanmar.
Zarni Myint ShweDepartment of Neurology, University of Medicine 1, Yangon General Hospital, Ministry of Health, Yangon 11111, Myanmar.
Kyaw Lwin ShowDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.ORCID 0000-0001-9349-5134
Nan Aye Thida OoDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.ORCID 0000-0002-1045-8790
Mya Thandar WinDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.
Khin Zarchi AungDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.
Win Pa Pa NaingDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.
Phyu Phyu LayDepartment of Neurology, University of Medicine 1, Yangon General Hospital, Ministry of Health, Yangon 11111, Myanmar.
Hlaing Myat ThuDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.
Zaw Than HtunDepartment of Medical Research, Ministry of Health, Yangon 11191, Myanmar.

Funding

Ministry of Health PRC017/2023
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe diagnosis of encephalitis is a challenging problem due to the heterogeneity of clinical presentations. The objective was to determine the etiology, clinical features, laboratory parameters, radiological findings, and in-hospital outcome of acute encephalitis syndrome (AES) cases in Myanmar.

methodsA prospective descriptive study was conducted at the Neuromedical Ward of Yangon General Hospital from March to August 2023. Eighty-one AES cases were enrolled, and cerebrospinal fluid (CSF) samples were collected. A Qiastat ME Panel was used to detect viral, bacterial, and fungal pathogens.

resultsSeventeen out of eighty-one (21%) cases were non-encephalitis with alternative definite diagnosis. Among the remaining 64 encephalitis cases, the exact infectious and immune etiologies were identified in 31 of 64 cases (48.4%); 26 of these (83.9%) were due to infectious causes and 5 (16.1%) were immune encephalitis. Among the infectious causes, six Herpes Simplex Virus-1-, one bacteriologically confirmed and seven probable

conclusionsHerpes encephalitis and tuberculous meningoencepalitis were the commonest. This study highlighted that molecular testing with a multidisciplinary approach is required to ensure the right treatment on time.

Indexed as

2023acute encephalitis syndromeadultautoimmune encephalitisinfectious causeMyanmar

Identifiers

PMID39410652
PMCPMC11475188

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