ReviewDiagnostics (Basel, Switzerland)2024
Superscan Pattern on Bone Scintigraphy: A Comprehensive Review.
Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06972628 (177Lu-PSMA-617), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
177Lu-PSMA-617 (Pluvicto) for the Treatment of Patients With Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Super Scan Bone Scan
Who cites it
11 citing papers in PubMed.
- From negative bone scintigraphy to oncologic superscan within five months: Explosive PSA kinetics in grade group 5 prostate adenocarcinoma.Urology case reports · 2026Article
- Diffuse osteosclerosis in a patient with systemic mastocytosis.JCEM case reports · 2026Article
- DoesEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Bone disease in kidney transplant: don't forget about osteomalacia: a case report and literature review.International urology and nephrology · 2026Review
- Deep Learning Based Computer-Aided Detection of Prostate Cancer Metastases in Bone Scintigraphy: An Experimental Analysis.Journal of imaging · 2026Article
- Efficacy and safety of Lutetium-177 (Annals of nuclear medicine · 2026Article
- Integrated diagnostic evaluation of multiple malignant neoplasms viaOncology letters · 2026Article
- Diffuse skeletal [Asia Oceania journal of nuclear medicine & biology · 2026Article
- Article
- Use of bone-SPECT/CT and Na[Frontiers in nuclear medicine · 2025Review
- Educational Case: Paget disease of bone.Academic pathologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesThe superscan pattern is a characteristic finding on bone scintigraphy, associated with a variety of metabolic bone diseases, malignancies, and other conditions. This pattern is characterized by a diffuse and intense uptake of radiotracer throughout the entire skeleton. Despite being a relatively rare finding, the superscan pattern can have significant clinical implications.
methodsThis comprehensive review summarizes the available literature on the superscan pattern, focusing on its pathophysiology, clinical significance, and differential diagnoses. Relevant studies and case reports were analyzed to outline the diagnostic challenges associated with the interpretation of bone scintigraphy featuring the superscan pattern.
resultsThe literature highlights the clinical significance of the superscan pattern in various metabolic and oncologic conditions. Misinterpretation of this pattern can lead to diagnostic challenges, especially in distinguishing it from other pathologic conditions. Differential diagnosis remains crucial in the accurate interpretation and subsequent management of patients with this finding.
conclusionsThis review provides a comprehensive overview of the superscan pattern on bone scintigraphy, aiming to assist clinicians in recognizing and managing this rare yet clinically important finding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.