Evidence map›Paper›PMID 39410610›Full record

ArticleDiagnostics (Basel, Switzerland)2024

The Management of Wound Healing in Infections after Hip Arthoplasty Using Stimulan and Negative Pressure Wound Therapy.

Florentin Dimofte, Cristina Dimofte, Sorin Ungurianu, Cristina Serban, George Țocu, Nicoleta Cârneciu, Iulia Filip, Laura Bezman, Ana Fulga, Dana Tutunaru and 5 more

Abstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Florentin DimofteGeneral Surgery Clinic, "St. Apostol Andrei" County Emergency Clinical Hospital, 800578 Galați, Romania.
Cristina DimofteDepartment Radiology, "Saint John" Emergency Children Hospital, Str. Gheorghe Asachi, Nr.2, 800487 Galați, Romania.
Sorin UngurianuDepartment of Morphological and Functional Sciences, Faculty of Medicine "Dunarea de Jos", 800008 Galați, Romania.
Cristina SerbanGeneral Surgery Clinic, "St. Apostol Andrei" County Emergency Clinical Hospital, 800578 Galați, Romania.
George ȚocuGeneral Surgery Clinic, "St. Apostol Andrei" County Emergency Clinical Hospital, 800578 Galați, Romania.
Nicoleta CârneciuGeneral Surgery Clinic, "St. Apostol Andrei" County Emergency Clinical Hospital, 800578 Galați, Romania.
Iulia FilipGeneral Surgery Clinic, "St. Apostol Andrei" County Emergency Clinical Hospital, 800578 Galați, Romania.
Laura BezmanDepartment of Ophtalmology, Faculty of Medicine "Dunarea de Jos", 800008 Galati, Romania.ORCID 0000-0002-2327-1220
Ana FulgaDepartment of Morphological and Functional Sciences, Faculty of Medicine "Dunarea de Jos", 800008 Galați, Romania.
Dana TutunaruDepartment of Laboratory Medicine, Faculty of Medicine "Dunarea de Jos", 800008 Galați, Romania.
Irina Mihaela AbdulanDepartment of Medical Specialties I, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Bogdan Mihnea CiuntuDepartment of General Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Raul MihailovDepartment of General Surgery, Faculty of Medicine "Dunarea de Jos", 800008 Galati, Romania.ORCID 0000-0001-7081-9490
Alin Mihai VasilescuDepartment of General Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Dorel FirescuDepartment of General Surgery, Faculty of Medicine "Dunarea de Jos", 800008 Galati, Romania.ORCID 0009-0002-0133-470X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundmedical teams continue to face challenges with infections following hip replacement surgery, whether they occur shortly after the procedure or months or years later. Certain medical conditions like diabetes, rheumatoid arthritis, and obesity are risk factors that make patients more susceptible to infections. Traditional intervention methods such as DAIR, one-step, or two-step procedures are being enhanced and refined to ensure quicker and more effective treatment. Some cases present particularly difficult challenges, featuring persistent fistulas and unpredictable responses to treatment.

methodsin our article, we share two unique cases, detailing their histories, progressions, and treatment decisions. We explore the use of antibiotic-impregnated calcium biocomposite as a local adjuvant therapy and the application of negative pressure therapy to expedite healing. The system of NWPT has seen widespread uptake and is now implemented routinely for open wounds, such as open fractures, fasciotomies, ulcers, and infected wounds.

resultsour findings demonstrate that surgical debridement and calcium sulfate bead insertion successfully treat bone and joint infections without causing any side effects or complications. As a particularity, in the first case, we encountered the exteriorization of Stimulan pearls after surgery, without other complications related to the biocomposite.

conclusionswe have found that NPWT is a beneficial tool in managing complex wounds in both acute and chronic stages, after the infection is cured, reducing the need for frequent dressing changes, shortening hospital stays, and enhancing patient comfort.

Indexed as

biocompositehip arthroplastyinfectionnegative pressure wound therapy

Identifiers

PMID39410610
PMCPMC11475829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.