Evidence map›Paper›PMID 39410353›Full record

ReviewMaterials (Basel, Switzerland)2024

An Up-to-Date Review of Materials Science Advances in Bone Grafting for Oral and Maxillofacial Pathology.

Carmen-Larisa Nicolae, Diana-Cristina Pîrvulescu, Adelina-Gabriela Niculescu, Dragoș Epistatu, Dan Eduard Mihaiescu, Alexandru Mihai Antohi, Alexandru Mihai Grumezescu, George-Alexandru Croitoru

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carmen-Larisa NicolaeFaculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Diana-Cristina PîrvulescuFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Adelina-Gabriela NiculescuFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-8968-504X
Dragoș EpistatuFaculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Dan Eduard MihaiescuFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-9873-3912
Alexandru Mihai AntohiFaculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alexandru Mihai GrumezescuFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-3036-094X
George-Alexandru CroitoruFaculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0005-9277-1797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone grafting in oral and maxillofacial surgery has evolved significantly due to developments in materials science, offering innovative alternatives for the repair of bone defects. A few grafts are currently used in clinical settings, including autografts, xenografts, and allografts. However, despite their benefits, they have some challenges, such as limited availability, the possibility of disease transmission, and lack of personalization for the defect. Synthetic bone grafts have gained attention since they have the potential to overcome these limitations. Moreover, new technologies like nanotechnology, 3D printing, and 3D bioprinting have allowed the incorporation of molecules or substances within grafts to aid in bone repair. The addition of different moieties, such as growth factors, stem cells, and nanomaterials, has been reported to help mimic the natural bone healing process more closely, promoting faster and more complete regeneration. In this regard, this review explores the currently available bone grafts, the possibility of incorporating substances and molecules into their composition to accelerate and improve bone regeneration, and advanced graft manufacturing techniques. Furthermore, the presented current clinical applications and success stories for novel bone grafts emphasize the future potential of synthetic grafts and biomaterial innovations in improving patient outcomes in oral and maxillofacial surgery.

Indexed as

biomaterialsbone defectsbone graftbone repairgrowth factorsmaxillofacial surgerynanoparticles

Identifiers

PMID39410353
PMCPMC11478239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.