Evidence map›Paper›PMID 39410168›Full record

ArticleFoods (Basel, Switzerland)2024

Pentacyclic Triterpenoid Content in Cranberry Raw Materials and Products.

Liang Xue, Bianca Carreiro, Md Sagir Mia, Inke Paetau-Robinson, Christina Khoo, Catherine Neto

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Cranberry Pomace Valorization: Composition, Extraction, Bioactivity, and Food Applications.Comprehensive reviews in food science and food safety · 2026
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liang XueDepartment of Chemistry and Biochemistry and Cranberry Health Research Center, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.ORCID 0000-0001-7071-9545
Bianca CarreiroDepartment of Chemistry and Biochemistry and Cranberry Health Research Center, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.
Md Sagir MiaDepartment of Chemistry and Biochemistry and Cranberry Health Research Center, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.
Inke Paetau-RobinsonOcean Spray Cranberries, Inc., Lakeville, MA 02349, USA.
Christina KhooOcean Spray Cranberries, Inc., Lakeville, MA 02349, USA.ORCID 0000-0001-6149-3820
Catherine NetoDepartment of Chemistry and Biochemistry and Cranberry Health Research Center, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.ORCID 0000-0002-4542-0880

Funding

Massachusetts Department of Public Health INTF4005HH2W22030280Ocean Spray Cranberries, Inc. 32922
6 · The paper itself

Abstract

Cranberry fruit extracts have been shown to inhibit expression of pro-inflammatory cytokines in THP-1 cells and reduce colonic tumor burden and tissue inflammation in a mouse model of colitis. These activities are attributed to both the triterpenoid and polyphenol constituents of the fruit. The pentacyclic triterpenoids ursolic acid (UA), oleanolic acid (OA), corosolic acid (CA), maslinic acid (MA), and esters of UA and OA occur in the waxy layer of cranberry peel, and their content in cranberry products is likely to vary with the fruit source and processing methods. UPLC-MS (ultra performance liquid chromatography-mass spectrometry) was applied to determine the four triterpenoid acids and their esters in cranberry products and raw materials. Cranberry pomace, a side stream in juice production, was a rich source at 64,090 µg total triterpenoids/g DW. Cranberry juice beverages ranged from 0.018 to 0.26 µg/g of product, fruit samples ranged from 6542 to 17,070 µg/g DW, and whole berry products contained up to 2665 µg/g DW. Free UA was the most plentiful triterpenoid in all samples. These analyses illustrate the potential value of an underutilized side stream in cranberry juice production and highlight potential benefits of whole fruit products.

Indexed as

cranberry juicecranberry pomacejuice processingoleanolic acidtriterpenoidsursolic acid

Identifiers

PMID39410168
PMCPMC11475460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.