ArticleFoods (Basel, Switzerland)2024
Preparation and Characterization Study of Zein-Sodium Caseinate Nanoparticle Delivery Systems Loaded with Allicin.
Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Garlic-Extract-Functionalized FeGels (Basel, Switzerland) · 2026Article
- Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review).Experimental and therapeutic medicine · 2026Review
- Mannosylated nanocarriers: a precision targeting strategy for tumors and infectious diseases.Frontiers in pharmacology · 2026Review
- Preparation and Characterization ofMolecules (Basel, Switzerland) · 2025Article
- Article
- Green Synthesis of Selenium Nanoparticles by Grape Seed Extract Synergized with Ascorbic Acid: Preparation Optimization, Structural Characterization, and Functional Activity.Foods (Basel, Switzerland) · 2025Article
- Investigation of Self-Assembled Flexible Zein Nanoparticles and Their Sensitivity to Complex Environments.Foods (Basel, Switzerland) · 2025Article
- Identification and functional characterization of AsWRKY9, a WRKY transcription factor modulating alliin biosynthesis in garlic (Allium sativum L.).BMC biology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Allicin, as a natural antibacterial active substance from plants, has great medical and health care value. However, due to its poor stability, its application in the field of food and medicine is limited. So, in this paper, allicin-zein-sodium caseinate composite nanoparticles (zein-Ali-SC) were prepared by antisolvent precipitation and electrostatic deposition. Through the analysis of the particle size, ζ-potential, encapsulation efficiency (EE), loading rate (LC) and microstructure, the optimum preparation conditions for composite nanoparticles were obtained. The mechanism of its formation was studied by fluorescence spectrum, Fourier infrared spectrum (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). The stability study results showed that the particle size of composite nanoparticles was less than 200 nm and its PDI was less than 0.3 under different NaCl concentrations and heating conditions, showing good stability. When stored at 4 °C for 21 days, the retention rate of allicin reached 61.67%, which was 52.9% higher than that of free allicin. After freeze-drying and reheating, the nanoparticles showed good redispersibility; meanwhile, antioxidant experiments showed that, compared with free allicin, the nanoparticles had stronger scavenging ability of free radicals, which provided a new idea for improving the stability technology and bioavailability of bioactive compounds.
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Registered trials
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