Evidence map›Paper›PMID 39410011›Full record

ArticleCancers2024

Phase I Clinical Trial on Pleural Mesothelioma Using Neoadjuvant Local Administration of Paclitaxel-Loaded Mesenchymal Stromal Cells (PACLIMES Trial): Study Rationale and Design.

Giulia Maria Stella, Daniela Lisini, Paolo Pedrazzoli, Giulia Galli, Chandra Bortolotto, Giulio Melloni, Gioacchino D'Ambrosio, Catherine Klersy, Amelia Grosso, Francesca Paino and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Giulia Maria StellaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.ORCID 0000-0003-0929-4394
Daniela LisiniCell Therapy Production Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0000-0002-7436-8401
Paolo PedrazzoliDepartment of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.ORCID 0000-0002-9419-7160
Giulia GalliDepartment of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.
Chandra BortolottoDiagnostic Imaging Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-9193-9309
Giulio MelloniUnit of Thoracic Surgery, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Gioacchino D'AmbrosioPathology Unit, Department of Diagnostical Services and Imaging, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Catherine KlersyBiostatistics and Clinical Trial Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0003-0314-8548
Amelia GrossoUnit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Francesca PainoCRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Stefano TomaselliUnit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Laura SaracinoUnit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0003-3482-1459
Giulio AlessandriCRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Augusto PessinaCRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Elena GrignaniEnvironmental Research Center, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.
Vittorio RostiPhase 1 Clinical Trial Unit and Experimental Therapy, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0003-4195-2289
Angelo Guido CorsicoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.ORCID 0000-0002-8716-4694
Patrizia ComoliCell Factory, Pediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Francesco AgustoniDepartment of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.

Funding

Fondazione Regionale per la Ricerca Biomedica , PLAGENCELL project - A network for cell and gene therapies for devastating diseases (grant to A.G.C. and P.C.) PLAGENCELL
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cell therapylocal deliveryphase I studypleural mesothelioma

Identifiers

PMID39410011
PMCPMC11475395

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.