Evidence map›Paper›PMID 39409916›Full record

ArticleCancers2024

The Predictive Value of the Fibrinogen-Albumin-Ratio Index on Surgical Outcomes in Patients with Advanced High-Grade Serous Ovarian Cancer.

Magdalena Postl, Melina Danisch, Fridolin Schrott, Paul Kofler, Patrik Petrov, Stefanie Aust, Nicole Concin, Stephan Polterauer, Thomas Bartl

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Magdalena PostlDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.
Melina DanischDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0009-0003-0289-3738
Fridolin SchrottDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.
Paul KoflerDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0000-0001-7139-1481
Patrik PetrovDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0009-0005-9980-5312
Stefanie AustDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0000-0002-6760-949X
Nicole ConcinDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.
Stephan PolterauerDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0000-0002-9649-4505
Thomas BartlDepartment of Obstetrics and Gynecology, Division of General Gynecology and Gynecologic Oncology, Medical University Vienna, 1090 Vienna, Austria.ORCID 0000-0002-1938-1574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe present study evaluates predictive implications of the pretherapeutic Fibrinogen-Albumin-Ratio Index (FARI) in high-grade serous ovarian cancer (HGSOC) patients undergoing primary cytoreductive surgery.

methodsThis retrospective study included 161 patients with HGSOC International Federation of Gynecology and Obstetrics (FIGO) stage ≥ IIb, who underwent primary cytoreductive surgery followed by platinum-based chemotherapy. Associations between the FARI and complete tumor resection status were described by receiver operating characteristics, and binary logistic regression models were fitted.

resultsHigher preoperative FARI values correlated with higher ascites volumes (r = 0.371,

conclusionsThe FARI appears to act as a surrogate for higher intra-abdominal tumor load. After clinical validation, FARI could serve as a readily available serologic biomarker to complement preoperative patient assessment, helping to identify patients who are likely to achieve complete tumor resection during primary cytoreductive surgery.

Indexed as

albumincytoreductive surgeryFARIfibrinogenHGSOCneoadjuvant chemotherapyovarian cancertumor load

Identifiers

PMID39409916
PMCPMC11476045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.