Evidence map›Paper›PMID 39409845›Full record

ArticleAnimals : an open access journal from MDPI2024

Interdisciplinary Animal Research Ethics-Challenges, Opportunities, and Perspectives.

Marcel Mertz, Tatiana Hetzel, Karla Alex, Katharina Braun, Samuel Camenzind, Rita Dodaro, Svea Jörgensen, Erich Linder, Sara Capas-Peneda, Eva Ingeborg Reihs and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Animal models of chronic thromboembolic pulmonary hypertension.Animal models and experimental medicine · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Marcel MertzInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-4871-4219
Tatiana HetzelInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, 30625 Hannover, Germany.
Karla AlexSection Translational Medical Ethics, National Center for Tumor Diseases (NCT) Heidelberg, Department of Medical Oncology, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-7065-9201
Katharina BraunDepartment of Law, Freie Universität Berlin, 14195 Berlin, Germany.
Samuel CamenzindDepartment of Philosophy, University of Vienna, 1010 Vienna, Austria.ORCID 0000-0002-2227-2061
Rita DodaroDepartment of Philosophy and Humanities, Freie Universität Berlin, 14195 Berlin, Germany.
Svea JörgensenDepartment of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden.ORCID 0000-0002-9370-9929
Erich LinderMesserli Research Institute, University of Veterinary Medicine, 1210 Vienna, Austria.ORCID 0000-0003-4342-472X
Sara Capas-Penedai3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0167-8812
Eva Ingeborg ReihsKarl Chiari Lab for Orthopaedic Biology, Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-6614-7369
Vini TiwariInstitute of Neuronal Cell Biology, Technical University Munich, 81377 Munich, Germany.
Zorana TodorovićDepartment of Philosophy, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0009-0008-6025-2839
Hannes KahrassInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-0694-0354
Felicitas SelterInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-2652-1317

Funding

Federal Ministry of Education and Research 01GP2184
6 · The paper itself

Abstract

Can nonhuman animals be used for the benefit of humans in a scientifically and morally justified manner and, if yes, how? Based on our own experiences as scholars from various academic backgrounds, we argue that this question can only be answered as an interdisciplinary and international endeavor, considering insights from research ethics and animal ethics as well as scientific and legal aspects. The aim of this article is to contribute to the foundation of the emerging field of animal research ethics. In doing so, we describe the following seven phases of animal research experiments: ethical, legal and social presumptions (phase 0), planning (phase I), review (phase II), conduct of experiments (phase III), publication/dissemination (phase IV), further exploitation of results (phase V), and evaluation (phase VI). In total, 16 key ethical, legal, and practical challenges that an ethical framework for the use of animals in research needs to address are identified and analyzed. Finally, we characterize the following four meta-challenges and opportunities associated with animal research ethics as a field: (1) moral pluralism, (2) the integration of views and positions outside the laboratory, (3) international plurality of conduct, standards, and legal norms, and (4) interdisciplinary education.

Indexed as

3Rsanimal ethicsanimal ethics committeesanimal experimentationanimal lawharm–benefit analysis

Identifiers

PMID39409845
PMCPMC11475729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.