Evidence map›Paper›PMID 39409704›Full record

ArticleAnimals : an open access journal from MDPI2024

Stepwise Imperatives for Improving the Protection of Animals in Research and Education in Canada.

Kyrstin Lavelle, Karim Fouad, Judy Illes

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyrstin LavelleNeuroethics Canada, Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Karim FouadDepartment of Physical Therapy, Neuroscience and Mental Health Institute, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada.
Judy IllesNeuroethics Canada, Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we review the standard-setting tools of different levels of government in Canada for overseeing the care of animals used in science against a landscape of other international efforts. We find regulatory inconsistencies, argue that the related shortcomings are detrimental to the level of care afforded to animals, and offer suggestions for a centralized and proactive approach that could close the existing gaps. Given the resources, cost, and time it would take to transform the current system into a single cohesive one, the proposed approach is a stepwise one, and begins with the addition of two new Rs-Reflection and Responsiveness-to the existing 3Rs framework: Replacement, Refinement, and Reduction. Reflection emphasizes more continuous and specific attention to progress in the research pathway as it applies to animals than is currently required by institutional review and reporting; Responsiveness speaks to the immediate action that researchers can take responsively to that ongoing evaluation.

Indexed as

animalethicsresearch

Identifiers

PMID39409704
PMCPMC11475983

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.