Evidence map›Paper›PMID 39409201›Full record

ArticleSensors (Basel, Switzerland)2024

A Reconfigurable, Nonlinear, Low-Power, VCO-Based ADC for Neural Recording Applications.

Reza Shokri, Yarallah Koolivand, Omid Shoaei, Daniele D Caviglia, Orazio Aiello

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reza ShokriBiomedical Integrated Systems Lab, University of Tehran, Tehran 1439957131, Iran.
Yarallah KoolivandDepartment of Electronics, Khajeh Nasir Toosi University of Technology, Tehran 1631714191, Iran.
Omid ShoaeiBiomedical Integrated Systems Lab, University of Tehran, Tehran 1439957131, Iran.
Daniele D CavigliaDipartimento di Ingegneria Navale, Elettrica, Elettronica e delle Telecomunicazioni (DITEN), University of Genoa, 16145 Genoa, Italy.ORCID 0000-0002-2145-1869
Orazio AielloDipartimento di Ingegneria Navale, Elettrica, Elettronica e delle Telecomunicazioni (DITEN), University of Genoa, 16145 Genoa, Italy.ORCID 0000-0002-6938-9806

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural recording systems play a crucial role in comprehending the intricacies of the brain and advancing treatments for neurological disorders. Within these systems, the analog-to-digital converter (ADC) serves as a fundamental component, converting the electrical signals from the brain into digital data that can be further processed and analyzed by computing units. This research introduces a novel nonlinear ADC designed specifically for spike sorting in biomedical applications. Employing MOSFET varactors and voltage-controlled oscillators (VCOs), this ADC exploits the nonlinear capacitance properties of MOSFET varactors, achieving a parabolic quantization function that digitizes the noise with low resolution and the spikes with high resolution, effectively suppressing the background noise present in biomedical signals. This research aims to develop a reconfigurable, nonlinear voltage-controlled oscillator (VCO)-based ADC, specifically designed for implantable neural recording systems used in neuroprosthetics and brain-machine interfaces. The proposed design enhances the signal-to-noise ratio and reduces power consumption, making it more efficient for real-time neural data processing. By improving the performance and energy efficiency of these devices, the research contributes to the development of more reliable medical technologies for monitoring and treating neurological disorders. The quantization step of the ADC spans from 44.8 mV in the low-amplitude range to 1.4 mV in the high-amplitude range. The circuit was designed and simulated utilizing a 180 nm CMOS process; however, no physical prototype has been fabricated at this stage. Post-layout simulations confirm the expected performance. Occupying a silicon area is 0.09 mm

Indexed as

Analog-Digital ConversionBrainBrain-Computer InterfacesEquipment DesignHumansNeuronsNonlinear DynamicsSignal Processing, Computer-AssistedSignal-To-Noise Rationeural recording systemsnonlinear quantizationparabolic function ADCVCO-based ADC

Identifiers

PMID39409201
PMCPMC11479173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.