Evidence map›Paper›PMID 39409159›Full record

ArticleInternational journal of molecular sciences2024

Synthesis and Preliminary Studies for In Vitro Biological Activity of Two New Water-Soluble Bis(thio)carbohydrazones and Their Copper(II) and Zinc(II) Complexes.

Alessio Zavaroni, Elena Riva, Valentina Borghesani, Greta Donati, Federica Santoro, Vincenzo Maria D'Amore, Matteo Tegoni, Giorgio Pelosi, Annamaria Buschini, Dominga Rogolino and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessio ZavaroniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0002-9761-7247
Elena RivaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0009-0000-7621-3422
Valentina BorghesaniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0003-3109-8306
Greta DonatiDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano, 49, 80131 Napoli, Italy.ORCID 0000-0002-0311-1721
Federica SantoroDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano, 49, 80131 Napoli, Italy.ORCID 0009-0008-0269-2000
Vincenzo Maria D'AmoreDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano, 49, 80131 Napoli, Italy.ORCID 0000-0002-6460-3447
Matteo TegoniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0002-9621-0410
Giorgio PelosiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0002-7946-0602
Annamaria BuschiniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0002-9877-2767
Dominga RogolinoDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0003-2295-5783
Mauro CarcelliDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0001-5888-4556

Funding

University of Parma Bando di Ateneo 2023 per la ricerca
6 · The paper itself

Abstract

Research in the field of metallodrugs is continually increasing. However, it is often limited by the poor solubility in water of the metal complexes. To try to overcome this problem, the two new ligands bis-(sodium 3-methoxy-5-sulfonate-salicylaldehyde)thiocarbohydrazone (

Indexed as

Coordination ComplexesCopperHydrazonesSolubilityWaterZincAntineoplastic AgentsCell Line, TumorCell SurvivalCrystallography, X-RayHumansLigandsAntineoplastic AgentsCoordination ComplexesCopperHydrazonesLigandsWaterZinccopper(II) complexescytotoxic activitymetal complexesmetallodrugsthiocarbohydrazones

Identifiers

PMID39409159
PMCPMC11476552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.