ArticleInternational journal of molecular sciences2024
Descriptive Analysis of Common Fusion Mutations in Papillary Thyroid Carcinoma in Hungary.
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Molecular and clinicopathological characteristics ofHistology and histopathology · 2026Review
- False negative rate and concordance of ThyGeNEXT®+ThyraMIR® testing with post-thyroidectomy histopathology.Journal of clinical & translational endocrinology · 2025Article
- Plasma exchange as a rescue therapy for treatment-resistant thyroid storm with concurrent heart failure: a literature review based on a case report.International journal of emergency medicine · 2024Article
- Editorial for the Special Issue "Current Research on Cancer Biology and Therapeutics: 2nd Edition".International journal of molecular sciences · 2024Article
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Authors and funding
12 authors.
Funding
Abstract
Thyroid cancer is the most common type of endocrine malignancy. Papillary thyroid carcinoma (PTC) is its predominant subtype, which is responsible for the vast majority of cases. It is true that PTC is a malignant tumor with a very good prognosis due to effective primary therapeutic approaches such as thyroidectomy and radioiodine (RAI) therapy. However, we are often required to indicate second-line treatments to eradicate the tumor properly. In these scenarios, molecular therapies are promising alternatives, especially if specifically targetable mutations are present. Many of these targetable gene alterations originate from gene fusions, which can be found using molecular diagnostics like next-generation sequencing (NGS). Nonetheless, molecular profiling is far from being a routine procedure in the initial phase of PTC diagnostics. As a result, the mutation status, except for
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