Evidence map›Paper›PMID 39409076›Full record

ArticleInternational journal of molecular sciences2024

Role of Plasma Angiopoietin-1 and VEGF Levels as Potential Biomarkers in Chronic Central Serous Chorioretinopathy with Macular Neovascularization.

Michał Chrząszcz, Weronika Pociej-Marciak, Natalia Mackiewicz, Bożena Romanowska-Dixon, Marek Sanak, Sławomir Teper, Maciej Gawęcki, Izabella Karska-Basta

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michał ChrząszczClinic of Ophthalmology and Ocular Oncology, University Hospital, 31-501 Krakow, Poland.
Weronika Pociej-MarciakClinic of Ophthalmology and Ocular Oncology, University Hospital, 31-501 Krakow, Poland.
Natalia MackiewiczClinic of Ophthalmology and Ocular Oncology, University Hospital, 31-501 Krakow, Poland.
Bożena Romanowska-DixonClinic of Ophthalmology and Ocular Oncology, University Hospital, 31-501 Krakow, Poland.ORCID 0000-0003-4251-2533
Marek SanakMolecular Biology and Clinical Genetics Unit, Department of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, 31-501 Krakow, Poland.ORCID 0000-0001-7635-8103
Sławomir TeperClinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0002-0935-8880
Maciej GawęckiDobry Wzrok Ophthalmological Clinic, 80-280 Gdansk, Poland.ORCID 0000-0003-2901-0248
Izabella Karska-BastaClinic of Ophthalmology and Ocular Oncology, University Hospital, 31-501 Krakow, Poland.ORCID 0000-0001-7927-6277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the plasma levels of angiopoietin-1 and vascular endothelial growth factor (VEGF) and their association with macular neovascularization (MNV) in patients with chronic central serous chorioretinopathy (cCSC). Correlations between plasma cytokine levels, CSC duration, and mean choroidal thickness (CT) were also investigated. Of the 59 patients with cCSC, 10 patients with MNV secondary to cCSC and 10 patients with cCSC without MNV were enrolled in the study. The control group included 15 healthy volunteers matched for age, sex, smoking status, and comorbidities. Chronic CSC was diagnosed based on typical findings on swept-source optical coherence tomography (OCT), fundus fluorescein angiography, and indocyanine green angiography. Additionally, all patients underwent OCT angiography to help detect MNV. Plasma angiopoietin-1 and VEGF levels were assessed using multiplex immunoassay. The plasma angiopoietin-1 levels differed between the 3 groups (

Indexed as

Angiopoietin-1BiomarkersCentral Serous ChorioretinopathyTomography, Optical CoherenceVascular Endothelial Growth Factor AAdultCase-Control StudiesChronic DiseaseFemaleFluorescein AngiographyHumansMaleMiddle AgedAngiopoietin-1ANGPT1 protein, humanBiomarkersVascular Endothelial Growth Factor AVEGFA protein, humanangiopoietin-1central serous chorioretinopathymacular neovascularizationvascular endothelial growth factor

Identifiers

PMID39409076
PMCPMC11477195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.