Evidence map›Paper›PMID 39409029›Full record

ArticleInternational journal of molecular sciences2024

Impact of Epstein-Barr Virus Nuclear Antigen 1 on Neuroinflammation in PARK2 Knockout Mice.

Davide Cossu, Yuji Tomizawa, Sachiko Noda, Eiichi Momotani, Tamami Sakanishi, Hanna Okada, Kazumasa Yokoyama, Leonardo Antonio Sechi, Nobutaka Hattori

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Davide CossuDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.ORCID 0000-0002-0557-9467
Yuji TomizawaDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.ORCID 0000-0002-5462-6725
Sachiko NodaDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.
Eiichi MomotaniComparative Medical Research Institute, Tsukuba 305-0856, Japan.ORCID 0000-0003-4765-1866
Tamami SakanishiDivision of Cell Biology, Juntendo University, Tokyo 1138431, Japan.
Hanna OkadaDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.
Kazumasa YokoyamaDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.ORCID 0000-0002-0950-1093
Leonardo Antonio SechiDepartment of Biomedical Sciences, Sassari University, 07100 Sassari, Italy.ORCID 0000-0003-0566-2049
Nobutaka HattoriDepartment of Neurology, Juntendo University, Tokyo 1138431, Japan.ORCID 0000-0002-2034-2556

Funding

Japan Society for the Promotion of Science 23K14675PRIN 2022 202238WEHT
6 · The paper itself

Abstract

This study aimed to explore the intricate relationship between mitochondrial dysfunction, infection, and neuroinflammation, focusing specifically on the impact of pathogenic epitopes of the Epstein-Barr Virus (EBV) nuclear antigen 1 (EBNA1) in a mouse model of mitochondrial dysfunctions. The investigation included female middle-aged

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalEpstein-Barr Virus Nuclear AntigensMice, Inbred C57BLMice, KnockoutAnimalsFemaleMiceMyelin-Oligodendrocyte GlycoproteinNeuroinflammatory DiseasesUbiquitin-Protein LigasesEBV-encoded nuclear antigen 1Epstein-Barr Virus Nuclear AntigensMyelin-Oligodendrocyte Glycoproteinparkin proteinUbiquitin-Protein LigasesEpstein–Barr virusexperimental autoimmune encephalomyelitismitochondrial dysfunctionneuroinflammationPARK2 knockout mice

Identifiers

PMID39409029
PMCPMC11477094

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.