Evidence map›Paper›PMID 39408949›Full record

ArticleInternational journal of molecular sciences2024

Evidence of Neutrophils and Neutrophil Extracellular Traps in Human NMSC with Regard to Clinical Risk Factors, Ulceration and CD8

Linda-Maria Hildegard Moeller, Carsten Weishaupt, Fiona Schedel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Linda-Maria Hildegard MoellerDepartment of Dermatology, Skin Cancer Center, University Clinic Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Carsten WeishauptDepartment of Dermatology, Skin Cancer Center, University Clinic Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0003-1195-2106
Fiona SchedelDepartment of Dermatology, Skin Cancer Center, University Clinic Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0001-6096-4731

Funding

University of Muenster, Medical Faculty, Medizinerkolleg 22-0030
6 · The paper itself

Abstract

Non-melanoma skin cancers (NMSC), including basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and Merkel cell carcinoma (MCC), are increasingly common and present significant healthcare challenges. Neutrophil extracellular traps (NETs), chromatin fibers expulsed by neutrophil granulocytes, can promote immunotherapy resistance via an impairment of CD8

Indexed as

Basal Cell CarcinomaCarcinoma, Squamous CellCD8-Positive T-LymphocytesExtracellular TrapsNeutrophilsSkin NeoplasmsAgedAged, 80 and overCarcinoma, Merkel CellFemaleHumansLymphocytes, Tumor-InfiltratingMaleMiddle AgedNeutrophil InfiltrationRisk Factorsbasal cell carcinomacutaneous squamous cell carcinomacytotoxic T cellsMerkel cell carcinomaneutrophil extracellular trapsneutrophilsnon-melanoma skin cancer

Identifiers

PMID39408949
PMCPMC11476888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.