Unveiling the Role of Two Rhodopsin-like GPCR Genes in Insecticide-Resistant House Flies,

Juanjuan Xin, Dylan Brown, Yifan Wang, Xin Wang, Ming Li, Ting Li, Nannan Liu

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juanjuan XinDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.

Dylan BrownDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.

Yifan WangDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-1561-0587

Xin WangDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.

Ming LiDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-7578-4968

Ting LiDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-6004-4617

Nannan LiuDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.

Funding

AAES Hatch/Multistate Grants ALA015-1-10026, ALA015-1-16009

6 · The paper itself

Abstract

Insecticide resistance in insects, driven by the overexpression of P450 enzymes, presents a significant challenge due to the enhanced metabolic detoxification of insecticides. Although the transcriptional regulation of P450 genes is not yet fully understood, G-protein-coupled receptor (GPCR) genes have emerged as key regulators in this process. This study is the first to associate GPCR genes with insecticide resistance in

Indexed as

Cytochrome P-450 Enzyme SystemHousefliesInsecticide ResistanceInsecticidesReceptors, G-Protein-CoupledRhodopsinAnimalsAnimals, Genetically ModifiedGene Expression RegulationInsect ProteinsCytochrome P-450 Enzyme SystemInsecticidesInsect ProteinsReceptors, G-Protein-CoupledRhodopsincytochrome P450sgene mappingG-protein coupled receptors (GPCRs)house fliesinsecticide resistance

Identifiers

PMID39408947

DOI10.3390/ijms251910618

PMCPMC11477390

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.