Evidence map›Paper›PMID 39408937›Full record

ArticleInternational journal of molecular sciences2024

Total Iridoid Glycosides from

Qi Dong, Zhenhua Wang, Na Hu, Fangfang Tie, Zenggen Liu, Ying Sun, Yue Wang, Nixia Tan, Honglun Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qi DongQinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.ORCID 0000-0002-6192-1597
Zhenhua WangCollege of Life Sciences, Yantai University, Yantai 264005, China.ORCID 0000-0002-7347-8561
Na HuQinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.
Fangfang TieQinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.
Zenggen LiuQinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.
Ying SunCollege of Life Sciences, Yantai University, Yantai 264005, China.
Yue WangMedical College, Qinghai University, Xining 810016, China.
Nixia TanMedical College, Qinghai University, Xining 810016, China.
Honglun WangQinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.ORCID 0000-0002-9882-9604

Funding

Qinghai Provincial Science and Technology Major Project 2023-SF-A5the Key project of Chinese Academy of Sciences under Grant ZDRW-ZS-2020-2
6 · The paper itself

Abstract

Cholestasis refers to a physiological and pathological process caused by bile acid (BA) overaccumulation inside the circulatory system and liver, leading to systemic and hepatocellular damage. Activating the farnesol X receptor (FXR) to restore BA homeostasis is a promising strategy for treating cholestasis. The objective of this research is to reveal solid evidence for the fact that the total iridoid glycosides from

Indexed as

CholestasisIridoid GlycosidesOxidative StressReceptors, Cytoplasmic and NuclearSwertia1-NaphthylisothiocyanateAnimalsMaleMolecular Docking SimulationRatsRats, Sprague-DawleyReceptor, Farnesoid X-Activated1-NaphthylisothiocyanateIridoid GlycosidesReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearcholestasisFXRiridoid glycosidesoxidative stressSwertia mussotii Franch.

Identifiers

PMID39408937
PMCPMC11476520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.