Evidence map›Paper›PMID 39408895›Full record

ArticleInternational journal of molecular sciences2024

GPX5-Enriched Exosomes Improve Sperm Quality and Fertilization Ability.

Jian Huang, Shuangshuang Li, Yuxuan Yang, Chen Li, Zixi Zuo, Rong Zheng, Jin Chai, Siwen Jiang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Perspectives in porcine semen conservation (liquid and frozen).The Journal of reproduction and development · 2026
    Review
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  11. Extracellular vesicles: key mediators inFrontiers in veterinary science · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jian HuangKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0009-0002-4153-7229
Shuangshuang LiKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Yuxuan YangKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Chen LiKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Zixi ZuoKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Rong ZhengKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Jin ChaiKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.
Siwen JiangKey Laboratory of Pig Genetics and Breeding of Ministry of Agriculture, Key Laboratory of Agricultural & Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China.

Funding

The Expert Workstation of Qingping Pig Farm in Dangyang City, Hubei Province,China 707123197
6 · The paper itself

Abstract

Semen preservation quality affects the artificial insemination success rate, and seminal exosomes are rich in various proteins that are transferable to sperm and conducive to sperm-function preservation during storage. However, the specific effects of these proteins remain unclear. In this study, the specific effects of these proteins on semen preservation quality and fertilization capacity were investigated through a proteomic analysis of seminal exosomes from boars with high conception rates (HCRs) and low conception rates (LCRs). The results revealed significant differences in the expression of 161 proteins between the two groups, with the GPX5 level being significantly higher in the HCR group (

Indexed as

ExosomesFertilizationGlutathione PeroxidaseSemen AnalysisSpermatozoaSperm MotilityAnimalsAntioxidantsMaleProteomicsSemen PreservationSperm CapacitationSwineAntioxidantsGlutathione Peroxidaseselenium-independent glutathione peroxidaseexosomesGPX5liquid storagesemen

Identifiers

PMID39408895
PMCPMC11477019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.