Evidence map›Paper›PMID 39408853›Full record

ArticleInternational journal of molecular sciences2024

Immunomodulatory Effect of Adipose Stem Cell-Derived Extra-Cellular Vesicles on Cytokine Expression and Regulatory T Cells in Patients with Asthma.

Jae Hoon Jung, Shin Ae Kang, Ji-Hwan Park, Sung-Dong Kim, Hak Sun Yu, Sue Jean Mun, Kyu-Sup Cho

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jae Hoon JungDepartment of Otorhinolaryngology, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
Shin Ae KangDepartment of Environmental Medical Biology, Catholic Kwandong University College of Medicine, Gangneung 25601, Republic of Korea.ORCID 0000-0001-9934-9787
Ji-Hwan ParkDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0001-9301-6957
Sung-Dong KimDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan 49241, Republic of Korea.
Hak Sun YuDepartment of Parasitology and Tropical medicine, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
Sue Jean MunDepartment of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.ORCID 0000-0003-4486-7178
Kyu-Sup ChoDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0002-8436-5722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are as effective as MSCs in the suppression of allergic airway inflammation, few studies have evaluated the immunomodulatory capacity of MSC-derived EVs in patients with asthma. Thus, we assessed the effects of adipose stem cell (ASC)-derived EVs on cytokine expression and regulatory T cells (Tregs) in peripheral blood mononuclear cells (PBMCs) of asthmatic patients. PBMCs (1 × 10

Indexed as

AsthmaCytokinesExtracellular VesiclesT-Lymphocytes, RegulatoryAdipose TissueAdultCells, CulturedFemaleHumansImmunomodulationLeukocytes, MononuclearMaleMesenchymal Stem CellsMiddle AgedCytokinesasthmaextracellular vesiclesimmunosuppression therapymesenchymal stem cellsregulatoryT lymphocytes

Identifiers

PMID39408853
PMCPMC11477288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.