Defects in the Maturation of Mitochondrial Iron-Sulfur Proteins: Biophysical Investigation of the MMDS3 Causing Gly104Cys Variant of IBA57.

Beatrice Bargagna, Tommaso Staderini, Steven H Lang, Lucia Banci, Francesca Camponeschi

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beatrice BargagnaDepartment of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0001-6933-7478

Tommaso StaderiniDepartment of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0001-6993-4408

Steven H LangDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-4369-7082

Lucia BanciDepartment of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0003-0562-5774

Francesca CamponeschiDepartment of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0002-4122-4508

Funding

ECOG OPERATIONS OFFICE (IBCSG)U10CA021115 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI COMIS, ROBERT L · 1985 to 2013

$132.6M

NCI NIH HHS U10 CA021115

6 · The paper itself

Abstract

Multiple mitochondrial dysfunctions syndrome type 3 (MMDS3) is a rare autosomal recessive mitochondrial leukoencephalopathy caused by biallelic pathogenic variants in the

Indexed as

Iron-Sulfur ProteinsMitochondrial ProteinsCarrier ProteinsHumansMitochondriaMitochondrial DiseasesMutationQb-SNARE ProteinsCarrier ProteinsIBA57 protein, humanIron-Sulfur ProteinsISCA2 protein, humanMitochondrial ProteinsQb-SNARE ProteinsVTI1A protein, humanIBA57iron–sulfur cluster biogenesisiron–sulfur clustersISCA2ISC machinerymitochondriaMMDS3multiple mitochondrial dysfunctions syndrome

Identifiers

PMID39408793

DOI10.3390/ijms251910466

PMCPMC11476781

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.