Evidence map›Paper›PMID 39408765›Full record

ArticleInternational journal of molecular sciences2024

Testing Green Tea Extract and Ammonium Salts as Stimulants of Physical Performance in a Forced Swimming Rat Experimental Model.

Ekaterina A Korf, Artem V Novozhilov, Igor V Mindukshev, Andrey S Glotov, Igor V Kudryavtsev, Ekaterina V Baidyuk, Irina A Dobrylko, Natalia G Voitenko, Polina A Voronina, Samarmar Habeeb and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Albumin Is an Integrative Protein of Blood Plasma and Beyond.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ekaterina A KorfSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Artem V NovozhilovSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Igor V MindukshevSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.ORCID 0000-0001-5978-2105
Andrey S GlotovD.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, St. Petersburg 199034, Russia.ORCID 0000-0002-7465-4504
Igor V KudryavtsevInstitute of Experimental Medicine, St. Petersburg 197022, Russia.
Ekaterina V BaidyukSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.ORCID 0000-0002-4108-9932
Irina A DobrylkoSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Natalia G VoitenkoSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.ORCID 0000-0002-3164-4971
Polina A VoroninaSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Samarmar HabeebSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Afrah GhanemSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.
Natalia S OsinovskayaD.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, St. Petersburg 199034, Russia.ORCID 0000-0001-7831-9327
Maria K SerebryakovaInstitute of Experimental Medicine, St. Petersburg 197022, Russia.
Denis V KrivorotovResearch Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical Biological Agency, p.o. Kuz'molovsky bld.93, St. Petersburg 188663, Russia.
Richard O JenkinsLeicester School of Allied Health Sciences, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Nikolay V GoncharovSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Torez 44, St. Petersburg 194223, Russia.

Funding

Sechenov Institute of Evolutionary Physiology and Biochemistry State Reserves of IEPhB RAS No. 075-00264-24-00
6 · The paper itself

Abstract

The study of drugs of natural origin that increase endurance and/or accelerate recovery is an integral part of sports medicine and physiology. In this paper, decaffeinated green tea extract (GTE) and two ammonium salts-chloride (ACL) and carbonate (ACR)-were tested individually and in combination with GTE as stimulants of physical performance in a forced swimming rat experimental model. The determined parameters can be divided into seven blocks: functional (swimming duration); biochemistry of blood plasma; biochemistry of erythrocytes; hematology; immunology; gene expression of slow- and fast-twitch muscles (m. soleus, SOL, and m. extensor digitorum longus, EDL, respectively); and morphometric indicators of slow- and fast-twitch muscles. Regarding the negative control (intact animals), the maximum number of changes in all blocks of indicators was recorded in the GTE + ACR group, whose animals showed the maximum functional result and minimum lactate values on the last day of the experiment. Next, in terms of the number of changes, were the groups ACR, ACL, GTE + ACL, GTE and NaCl (positive control). In general, the number of identified adaptive changes was proportional to the functional state of the animals of the corresponding groups, in terms of the duration of the swimming load in the last four days of the experiment. However, not only the total number but also the qualitative composition of the identified changes is of interest. The results of a comparative analysis suggest that, in the model of forced swimming we developed, GTE promotes restoration of the body and moderate mobilization of the immune system, while small doses of ammonium salts, especially ammonium carbonate, contribute to an increase in physical performance, which is associated with satisfactory restoration of skeletal muscles and the entire body. The combined use of GTE with ammonium salts does not give a clearly positive effect.

Indexed as

Plant ExtractsSwimmingTeaAmmonium CompoundsAnimalsCarbonatesMaleMuscle, SkeletalPhysical Functional PerformanceRatsRats, WistarAmmonium CompoundsCarbonatesPlant ExtractsTeaammonium saltsbiochemical and immunological parameterscalcium balanceenduranceforced swimminggene expressiongreen tea extractm. extensor digitorum longusmorphometrym. soleusrats

Identifiers

PMID39408765
PMCPMC11477139

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.