Evidence map›Paper›PMID 39408641›Full record

ArticleInternational journal of molecular sciences2024

Phage Display Revealed the Complex Structure of the Epitope of the Monoclonal Antibody 10H10.

Daniil V Shanshin, Sophia S Borisevich, Olga N Shaprova, Valentina S Nesmeyanova, Alexander A Bondar, Yuri B Porozov, Edward M Khamitov, Evgeniia A Kolosova, Arseniya A Shelemba, Nikita D Ushkalenko and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniil V ShanshinState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.
Sophia S BorisevichLaboratory of Physical and Chemical Methods of Analysis, Ufa Institute of Chemistry UFRS RAS, Ufa 450054, Russia.ORCID 0000-0001-8481-0470
Olga N ShaprovaState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.
Valentina S NesmeyanovaState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0003-1091-3586
Alexander A BondarGenomics Core Facility, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.ORCID 0000-0001-9181-0487
Yuri B PorozovLaboratory of Angiopathology, The Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Street, Moscow 125315, Russia.ORCID 0000-0002-5450-3135
Edward M KhamitovLaboratory of Physical and Chemical Methods of Analysis, Ufa Institute of Chemistry UFRS RAS, Ufa 450054, Russia.ORCID 0000-0001-8987-4254
Evgeniia A KolosovaState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0002-8967-4719
Arseniya A ShelembaFederal State Budgetary Scientific Institution "Federal Research Center for Fundamental and Translational Medicine", Novosibirsk 630117, Russia.
Nikita D UshkalenkoState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0002-2171-7444
Elena V ProtopopovaState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0002-2782-8364
Artemiy A SergeevState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0002-3591-1571
Valery B LoktevState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0002-0229-321X
Dmitriy N ShcherbakovState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Russia.ORCID 0000-0001-8023-4453

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2019-1665
6 · The paper itself

Abstract

The annual number of reported human cases of flavivirus infections continues to increase. Measures taken by local healthcare systems and international organizations are not fully successful. In this regard, new approaches to treatment and prevention of flavivirus infections are relevant. One promising approach is to use monoclonal antibody preparations. The mouse mAb 10H10 is capable of interacting with viruses belonging to the genus

Indexed as

Antibodies, MonoclonalEpitopesAmino Acid SequenceAnimalsAntibodies, ViralCell Surface Display TechniquesDengue VirusEncephalitis Viruses, Tick-BorneEpitope MappingHumansMiceModels, MolecularPeptide LibraryViral Envelope ProteinsZika VirusAntibodies, MonoclonalAntibodies, ViralEpitopesPeptide LibraryViral Envelope Proteinschimeric antibodyflavivirusmonoclonal antibodyphage displayrecombinant proteins

Identifiers

PMID39408641
PMCPMC11476565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.