Evidence map›Paper›PMID 39408636›Full record

ArticleInternational journal of molecular sciences2024

Exploring the Role and Pathophysiological Significance of Aldehyde Dehydrogenase 1B1 (ALDH1B1) in Human Lung Adenocarcinoma.

Ilias Tsochantaridis, Dimitris Brisimis, Margaritis Tsifintaris, Anastasia Anastasiadou, Efthymios Lazos, Antreas Ermogenous, Sylia Christou, Nefeli Antonopoulou, Mihalis I Panayiotidis, Michail I Koukourakis and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ilias TsochantaridisDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-1607-7470
Dimitris BrisimisDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Margaritis TsifintarisDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-8603-3767
Anastasia AnastasiadouDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Efthymios LazosDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Antreas ErmogenousDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-5266-5237
Sylia ChristouDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0009-0002-4394-1030
Nefeli AntonopoulouDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-7008-4738
Mihalis I PanayiotidisDepartment of Cancer Genetics, Therapeutics & Ultrastructural Pathology, The Cyprus Institute of Neurology & Genetics, Nicosia 2371, Cyprus.ORCID 0000-0002-1450-3552
Michail I KoukourakisRadiotherapy/Oncology, Radiobiology & Radiopathology Unit, Department of Medicine, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-2324-699X
Alexandra GiatromanolakiDepartment of Pathology, University General Hospital of Alexandroupolis, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Aglaia PappaDepartment of Molecular Biology & Genetics, School of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-0913-4315

Funding

Operational Program "Competitiveness, Entrepreneurship & Innovation" (EPAnEK) co-funded by the European Regional Development Fund (ERDF) and national resources (Partner-ship Agreement 2014-2020). MIS Code 5047285
6 · The paper itself

Abstract

Aldehyde dehydrogenases (ALDHs) constitute a diverse superfamily of NAD(P)

Indexed as

Adenocarcinoma of LungAldehyde Dehydrogenase 1 FamilyEpithelial-Mesenchymal TransitionLung NeoplasmsA549 CellsAldehyde Dehydrogenase, MitochondrialCell Line, TumorCell MovementCell ProliferationDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHumansNeoplastic Stem CellsSignal TransductionAldehyde Dehydrogenase 1 FamilyAldehyde Dehydrogenase, MitochondrialALDH1B1 protein, humanA549aldehyde dehydrogenases (ALDHs)ALDH1B1cancer stem cells (CSCs)cell morphologycell proliferationchemoresistanceCSC-related pathwaysEMTlung adenocarcinomamigration

Identifiers

PMID39408636
PMCPMC11477306

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.