Evidence map›Paper›PMID 39408626›Full record

ArticleInternational journal of molecular sciences2024

Chromogranin B Protects Human Umbilical Endothelial Cells against Oxidative Stress.

Elena Grossini, Sakthipriyan Venkatesan, Mohammad Mostafa Ola Pour, Daniela Ferrante, Daniela Surico, Rosanna Vaschetto, Vincenzo Cantaluppi, Mario Pirisi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elena GrossiniLaboratory of Physiology, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-3012-259X
Sakthipriyan VenkatesanLaboratory of Physiology, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-7517-2574
Mohammad Mostafa Ola PourLaboratory of Physiology, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-8810-4688
Daniela FerranteStatistical Unit, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0003-4929-3759
Daniela SuricoGynecology and Obstetrics, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.
Rosanna VaschettoAnesthesia and Intensive Care, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0003-4625-4367
Vincenzo CantaluppiNephrology Unit, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-4120-3555
Mario PirisiInternal Medicine Unit, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-9740-0155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromogranin B (CgB) is involved in the control of the cardiovascular system through the regulation of catecholamine release. Whether CgB can exert direct actions on the endothelium has not yet been clarified. Here, we aimed to investigate the effects of CgB on cell viability, mitochondrial membrane potential, reactive oxygen species (ROS), glutathione (GSH), nitric oxide (NO) release, and the cytosolic calcium concentration ([Ca

Indexed as

CalciumCell SurvivalGlutathioneHuman Umbilical Vein Endothelial CellsMembrane Potential, MitochondrialNitric OxideOxidative StressReactive Oxygen SpeciesCells, CulturedHumansHydrogen PeroxideCalciumGlutathioneHydrogen PeroxideNitric OxideReactive Oxygen Speciescardiovasculargraninesmitochondrianitric oxideoxidative stressprotection

Identifiers

PMID39408626
PMCPMC11476595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.