Evidence map›Paper›PMID 39408464›Full record

ReviewPolymers2024

Polyvinyl Alcohol (PVA)-Based Hydrogels: Recent Progress in Fabrication, Properties, and Multifunctional Applications.

Xiaoxu Liang, Hai-Jing Zhong, Hongyao Ding, Biao Yu, Xiao Ma, Xingyu Liu, Cheong-Meng Chong, Jingwei He

Abstract readReview
In one paragraph

Review in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed.

  1. Article
  2. Review
  3. Interfacial Redox Regulation of γ-AlGels (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Review
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoxu LiangSchool of Arts and Sciences, Guangzhou Maritime University, Guangzhou 510725, China.ORCID 0000-0002-3252-3418
Hai-Jing ZhongState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-1247-3150
Hongyao DingCollege of Materials Science and Engineering, Nanjing Tech University, Nanjing 210009, China.ORCID 0000-0003-1209-4182
Biao YuSchool of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524048, China.
Xiao MaSchool of Arts and Sciences, Guangzhou Maritime University, Guangzhou 510725, China.
Xingyu LiuSchool of Arts and Sciences, Guangzhou Maritime University, Guangzhou 510725, China.
Cheong-Meng ChongState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Jingwei HeSchool of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China.

Funding

Key Laboratory of Prevention, Diagnosis and Therapy of Upper Gastrointestinal Cancer of Zhejiang Province 2022SXHD0003Key Laboratory of Sichuan Province for Traditional Chinese Medicine Regimen and Health & Key Laboratory of State Administration of Traditional Chinese Medicine for Sci-entific Research & Industrial Development of Traditional Chinese Medicine Regimen and H GZ2022003the Guangdong Basic and Applied Basic Research Foundation (China) No. 2024A1515010167the Guangzhou Basic and Applied Basic Research Foundation (China) 2023A03J0616the National Natural Science Foundation of China No. 82204482the Research Fund of University of Macau File no. MYRG-GRG2023-00048-ICMSthe Science and Technology Development Fund, Macau S.A.R (FDCT) File no. 0060/2023/ITP2the Start-up Research Foundation from Guangzhou Maritime University/Guangzhou Jiaotong University (under Preparation) No. K42022103the Tertiary Education Scientific research project of Guangzhou Municipal Education Bureau No. 2024312331Young Elite Scientists Sponsorship Program by CACM (China) No. 2021-QNRC2-B22
6 · The paper itself

Abstract

Polyvinyl alcohol (PVA)-based hydrogels have attracted significant attention due to their excellent biocompatibility, tunable mechanical properties, and ability to form stable three-dimensional networks. This comprehensive review explores the recent advancements in PVA-based hydrogels, focusing on their unique properties, fabrication strategies, and multifunctional applications. Firstly, it discusses various facile synthesis techniques, including freeze/thaw cycles, chemical cross-linking, and enhancement strategies, which have led to enhanced mechanical strength, elasticity, and responsiveness to external stimuli. These improvements have expanded the applicability of PVA-based hydrogels in critical areas such as biomedical, environmental treatment, flexible electronics, civil engineering, as well as other emerging applications. Additionally, the integration of smart functionalities, such as self-healing capabilities and multi-responsiveness, is also examined. Despite progress, challenges remain, including optimizing mechanical stability under varying conditions and addressing potential toxicity of chemical cross-linkers. The review concludes by outlining future perspectives, emphasizing the potential of PVA-based hydrogels in emerging fields like regenerative medicine, environmental sustainability, and advanced manufacturing. It underscores the importance of interdisciplinary collaboration in realizing the full potential of these versatile materials to address pressing societal challenges.

Indexed as

biomedicalenvironmental treatmentfabricationflexible devicepolyvinyl alcohol-based hydrogels

Identifiers

PMID39408464
PMCPMC11478944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.